Meghan Moran

Methods Animal husbandry. All procedures and training of research staff for this project were approved and in compliance with the Institutional Animal Care and Use Committee (IACUC) at Rush University Medical Center (Protocol 21–077). A total of 44 male Sprague Dawley (SD) rats (375-400g, approximately 4 months old, Envigo) were pair-housed in cages (polysulfone,19 × 10.5 × 8 in.) in the animal facility maintained at 22°C and 35%−55% humidity with a 12-hour light/dark cycle (light 7 AM-7 PM).

Background Aims and Hypotheses Aim 1: To Test CBT and Mindfulness or ACT Intervention Message Efficacy for Reducing Momentary Smoking Urges (n=80) Aim 2: To Test if Exposure to Urge Reduction Messages Results in Changes in Smoking Behavior Over Time Compared With an EMA-Only Control Group (n=80) Aim 3: Explore Moderation Effects of Substance Co-Use (Cannabis, Alcohol, Other Drugs) and Exposure to Specific Location (Home, Work, Bars) on Urge Reduction Message Efficacy Overview of Design...

Abstract Disrupted intestinal epithelial barrier function has been proposed to be integral to rheumatoid arthritis (RA) progression and pathogenesis. To further define the molecular pathways in synovial inflammation and the response of the intestinal tissues, we have used a rat model of mono-joint inflammatory arthritis, induced by intra-articular injection of Complete Freunds adjuvant (CFA).