Melanie Shpigel

Introduction Primary malignant melanoma of the colon is an extremely rare neoplasm of the gastrointestinal tract, the diagnosis of which poses a significant clinical challenge due to the nonspecificity of clinical symptoms and lack of clear diagnostic algorithms. The difficulty of verification stems from the need to distinguish primary intestinal mucosal lesions from metastatic lesions from an unknown primary site.

CAR T-cell therapy has emerged as a viable treatment for patients with diffuse large B-cell lymphoma (DLBCL), offering significantly enhanced survival with manageable safety to optimize outcomes for this group. While the advantages are unmistakable, many considerations emerge when considering when and where to treat patients, especially those with relapsed/refractory disease, in the treatment landscape.

Chinmay Jani, MD, joined CancerNetwork® in the studio to discuss different aspects of his work dedicated to advancing precision medicine in oncology. He highlighted ongoing research and studies focused on artificial intelligence (AI)–based tools in oncologic decision-making as well as overcoming immunotherapy resistance among those with lung cancer.