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Melody C. Iacino on Muck Rack

Melody C. Iacino

As seen in: Cell Reports, eLife
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Articles

Cholinergic input to mouse visual cortex signals a movement state and acutely enhances layer 5 responsiveness

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By Georg B. Keller, Melody C. Iacino, Daniel Hoops, Jingjing Liu
| eLife
All data analysis was done using custom scripts written in MATLAB (MathWorks). To quantify the average population response traces, we first calculated the average event-triggered fluorescence trace for each region of interest (ROI). The responses of all ROIs was then averaged and baseline-subtracted. Locomotion onset was defined as locomotion velocity crossing a threshold of 0.25 cm/s for at least 1 s, while having been below the threshold for 1 s before.
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Behavior: Prompting social investigation

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By Emma F Keppler, Susanna Molas, Maha Rashid, Melody C. Iacino
| eLife
Animals often need to assess whether a member of their species (a conspecific) that they have not met before will be a friend or a foe. As such, most adult animals would tend to investigate an unfamiliar peer over one which they were already acquainted with (Tapper and Molas, 2020). Deciding whether and how to engage with an unknown individual relies on multiple levels of analysis underpinned by different brain networks and areas.
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A unique multi-synaptic mechanism involving acetylcholine and GABA regulates dopamine release in the nucleus accumbens through early adolescence in male rats

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By Melody C. Iacino, Taylor A. Stowe, Elizabeth G. Pitts, Lacey L Sexton
| eLife
Accepted manuscript, PDF only. Full online edition to follow. Author Accepted Manuscript PDF only version. The full online version will follow soon. Accepted Manuscript published June 11, 2024 (This version) Accepted June 10, 2024 Received September 10, 2020 Share this article Cite this article A unique multi-synaptic mechanism involving acetylcholine and GABA regulates dopamine release in the nucleus accumbens through early adolescence in male rats eLife 13:e62999.
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