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Meshi Barsheshet on Muck Rack

Meshi Barsheshet

As seen in: Cell Press
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Articles

Hierarchy in Hfq Chaperon Occupancy of Small RNA Targets Plays a Major Role in Their Regulation

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By Raya Faigenbaum-Romm, Yair E. Gatt, Avichai Reich, Meshi Barsheshet
| Cell Press Verified
Highlights • Basic concepts of regulation by small RNAs are revealed from large-scale data • Small changes in the small RNA sequence shift the target repertoire accordingly • A regulatory sRNA affects the expression levels of only a subset of its targets • Competition among targets over Hfq binding plays a major role in their regulation Summary Bacterial small RNAs (sRNAs) are posttranscriptional regulators of gene expression that base pair with complementary sequences on target mRNAs, often...
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