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Metabolomics Core

As seen in: Nature, Oxford University Press (OUP), PLOS ONE, Frontiers, Molecular Cancer, Cell Chemical Biology, Cell Press, TechTrends
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Articles

CAR signaling instructs divergent metabolic reprogramming and functional fates in αβ and γδ T cells

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By Metabolomics Core, Martinez Planes, Renata Ariza Marques
| TechTrends
Wang CQ, Lim PY, Tan AH. Gamma/delta T cells as cellular vehicles for anti-tumor immunity. Front Immunol. 2023;14:1282758. CAS PubMed Google Scholar Garber K. gammadelta T cells bring unconventional cancer-targeting to the clinic - again. Nat Biotechnol. 2020;38:389–91. CAS PubMed Google Scholar Raverdeau M, Cunningham SP, Harmon C, Lynch L. gammadelta T cells in cancer: a small population of lymphocytes with big implications. Clin Transl Immunol. 2019;8:e01080.
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Integrative proteomics reveals MSH6 to modulate PARP inhibitor sensitivity in BRCA1/2 -proficient ovarian cancer

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By Ou Deng, Bin Fang, Metabolomics Core
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Deng O, Nepomuceno TDC, Fang B, Welsh EA, Izumi V, Martin RH, et al. (2026) Integrative proteomics reveals MSH6 to modulate PARP inhibitor sensitivity in BRCA1/2-proficient ovarian cancer. PLoS One 21(9): e0357365. https://doi.org/10.1371/journal.pone.0357365 Editor: Giovanni Nassa, University of Salerno, ITALY Received: April 2, 2026; Accepted: August 17, 2026; Published: September 2, 2026 Copyright: © 2026 Deng et al.
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Effects of GDF6 on active protein synthesis by cells of degenerated intervertebral disc - European Spine Journal

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By Hong Kong S.A.R, Metabolomics Core
| link.springer.com
Abstract Intervertebral disc degeneration (IVD) is a leading cause of low back pain, a prevalent musculoskeletal condition. IVD degeneration is characterized by the degradation of nucleus pulposus (NP), annulus fibrosus (AF), and cartilage endplates (EP). Growth Differentiation Factor 6 (GDF6), part of the bone morphogenetic protein family, has demonstrated potential in maintaining disc integrity. However, its precise role in cellular protein synthesis during IVD degeneration remains unclear.
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