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Articles by Michael Roy
Design and Performance Assessment of High-Level Waste Disposal Canisters
Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References 1 Nagra., “ Rahmenbewilligungsgesuch für das Geologisches Tiefenlager – Sicherheitsbericht.” Nagra Technischer Bericht NTB 24-01 (Nagra, 2025). 2, , , et al., “WP15 ConCorD State-of-the-Art Report (Container Corrosion Under Disposal Conditions,” Frontiers in Nuclear Engineering 3 (2024): 1404739.
Implementing the Quantum Fourier Transform on a molecular qudit with full refocusing and state tomography
Abstract Molecular spin qudits based on lanthanide complexes offer a promising platform for quantum technologies, combining chemical tunability with multi-level encoding. However, experimental demonstrations of their envisaged capabilities remain scarce, posing the difficulty of achieving precise control over coherences between qudit states in long pulse sequences.
Accurate PROTAC targeted degradation prediction with DegradeMaster
Abstract Motivation: Proteolysis-targeting chimeras (PROTACs) are heterobifunctional molecules that can degrade "undruggable" protein of interest (POI) by recruiting E3 ligases and hijacking the ubiquitin-proteasome system. Some efforts have been made to develop deep learning-based approaches to predict the degradation ability of a given PROTAC.
A Four‐Coordinate Pr4+ Imidophosphorane Complex
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
A Four‐Coordinate Pr4+ Imidophosphorane Complex
An imidophosphorane ligand framework provided one of the first structurally authenticated examples of molecular Tb4+,1 and the in situ characterization of Pr4+.2 The tetravalent oxidation state in molecular lanthanide (Ln) complexes has been documented in Tb1, 3 and Pr,2, 4 but remains largely confined to examples of Ce4+.5 Despite the similar thermodynamic accessibility of Pr4+ and Tb4+,5a multiple ligand systems which support isolable Tb4+ complexes yield fleeting Pr4+ complexes, precluding...
VMware Desktop Hypervisor Pro Apps Now Available for Personal Use
As we complete the integration of Fusion and Workstation into Broadcom, we wanted to share with the community some changes to our product lineup and how we deliver them to our users. Most importantly are changes to the way we license our desktop hypervisor products. From now onward, Fusion Pro and Workstation Pro will have two license models. We now provide a Free Personal Use or a Paid Commercial Use subscription for our Pro apps.
VMware Workstation Pro: Now Available Free for Personal Use
VMware Desktop Hypervisor products Fusion and Workstation are used by millions of people every day to run virtual machines on their Windows, Linux and Mac computers. They give users the ability to quickly and easily build “local virtual” environments to install other operating systems, learn about technology, build and test software, complex systems, browsers, apps, games, and more.
A range expanding ecosystem engineer influences historical and expanded habitats via the same causal pathways
Abstract Species are shifting their ranges in response to climate change. There remain many unknowns about relative impacts of range-expanding ecosystem engineers between historical and expanded habitats, however. The mud fiddler crab Minuca pugnax (=Uca pugnax) is shifting its range northward likely due to increased warming in the Gulf of Maine. A burrowing crab, M.
A New Chapter
Now that our acquisition by Broadcom has successfully completed, the integration into our new home is well underway. Our new Senior Vice President and General Manager Krish Prasad, who has been a long-time Desktop Hypervisor supporter, today published some news about how we’ll be transforming the VMware business within our new home at Broadcom.
Intervalence Charge Transfer in Nonbonding, Mixed-Valence, Homobimetallic Ytterbium Complexes
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2024, XXXX, XXX RETURN TO ARTICLES ASAPPREVArticleNEXT Michael D. Roy School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, United States , Thaige P.
Intervalence Charge Transfer in Nonbonding, Mixed-Valence, Homobimetallic Ytterbium Complexes
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2024, XXXX, XXX RETURN TO ARTICLES ASAPPREVArticleNEXT Michael D. Roy School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, United States , Thaige P.
What Makes Arabica Coffee Beans Unique in Flavor and Aroma?
In the vast world of coffee, one variety stands out for its exceptional flavor and aromatic qualities – Arabica coffee beans. Renowned for its mild, nuanced taste and enticing aroma, Arabica has become synonymous with high-quality coffee. This exploration delves into the distinctive features that set Arabica coffee beans apart from other coffee varieties. Arabica coffee, scientifically known as Coffea arabica, is a coffee plant species that originated in Ethiopia's high-altitude regions.
Fusion 13.5 Is Live!
For users on Fusion 13 already, you can update by clicking “Check For Updates” within the app. If you’re still on Fusion 12, head on over to store.vmware.com and upgrade to Fusion 13 today to get going right away. Want to try Fusion 13 Pro free for 30 days? Head over here! Want to use Fusion 13 Player for Personal Use? Get your Free Key here! We are thrilled to announce the launch of VMware Fusion 13.5 Pro and VMware Fusion 13.5 Player for Mac.
Current therapies and future prospective for locally aggressive mesenchymal tumors
Alessandra Maleddu1*, Jessica Zhu1, Michael Roy Clay2 and Breelyn Ann Wilky1 1Department of Medicine, University of Colorado School of Medicine, Aurora, CO, United States 2Department of Pathology, University of Colorado School of Medicine, Aurora, CO, United States Locally aggressive mesenchymal tumors comprise a heterogeneous group of soft tissue and bone tumors with intermediate histology, incompletely understood biology, and highly variable natural history.
Workstation Tech Preview 2023
Share on: 0 Ready for Testing It’s that time of year again! We’re aiming to get your feedback about some new features we’re looking to bring into the VMware Workstation product line this year. This Tech Preview focuses on more low-level functionality, like a new VM encryption scheme and improved programatic support for VMs with vTPMs (like Windows 11).
VMware Fusion Tech Preview 2023
We are thrilled to announce the release of VMware Fusion Tech Preview 2023, marking a significant leap forward for our virtualization software on macOS. With this release, we are dramatically improving our experience with Windows 11 on Fusion on Macs with Apple silicon and the new macOS Sonoma, while also unveiling subtle new functionality for working with encrypted virtual machines programmatically, as well as security enhancements.
Harnessing the Power of Information: An Introduction to OSINT
In an age where information is as precious as gold, a concept is rising in prominence in intelligence circles. Open Source Intelligence, often abbreviated as OSINT, refers to collecting information from publicly available sources for intelligence purposes. So, what is Open Source Intelligence? To simplify, OSINT is the art and science of gathering and analyzing data from open and publicly available sources to aid in decision-making.
Fueling Your Dreams: Small Business Loans for Entrepreneurs
Starting a small business requires passion, dedication, and the financial resources to turn your dreams into reality. For many entrepreneurs, securing a business loan is crucial in obtaining the necessary capital. However, what if you need more credit history? Don't worry! There are options available to help you overcome this hurdle. This article delves into the world of no credit business loans. So explore their importance and benefits as this guide navigates you through the lending landscape.
Secure Your Retirement: Investing in Gold with an IRA Account
Retirement planning is critical to securing financial stability in the golden years. One avenue worth exploring is investing in a gold IRA account. This article will delve into the world of gold IRAs and the benefits they offer in securing your retirement. Discover how investing in gold can provide a solid foundation for your future and safeguard your wealth against economic uncertainties. 1. Understanding Gold IRAs: What Are They?
AI Image Generators: Bridging the Gap Between Reality and Imagination
In the realm of technological advancements, AI image generators have emerged as a fascinating innovation that blurs the line between reality and imagination. These powerful tools, driven by artificial intelligence, have the ability to create highly realistic and visually captivating images. They hold immense potential in various fields, from entertainment and design to research and simulation.
Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling - Nature Communications
Abstract PEAK pseudokinases regulate cell migration, invasion and proliferation by recruiting key signaling proteins to the cytoskeleton. Despite lacking catalytic activity, alteration in their expression level is associated with several aggressive cancers. Here, we elucidate the molecular details of key PEAK signaling interactions with the adapter proteins CrkII and Grb2 and the scaffold protein 14-3-3.
Editorial: Current use of virtual reality and e-therapy for the treatment of trauma and stress-related disorders
Recently, the use of virtual reality and technological innovations based on e-therapy have had a great impact on trauma and stress-related disorders, such as PTSD, allowing evidence-based interventions for these mental disorders. Given the technological advancements and the scope that these systems have shown in recent years, it is important to have updated treatment protocols based on new proven and effective technologies.
The effect of a virtual reality based intervention on processing speed and working memory in individuals with ADHD-A pilot-study
1 Introduction Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that manifests in children and adults and is characterized by high levels of inattention, hyperactivity, and impulsivity that often lead to multiple behavioral problems (Association American Psychiatric, 2014; Barkley, 2016). ADHD has a worldwide incidence in approximately 5% in children and 2.5% in adults (Polanczyk et al., 2014).
Microsoft Now Officially Supports Windows on Mac computers with Apple silicon
Exciting news out of Redmond today as Microsoft has expressed commitment to fully support Windows on Arm in virtual machines on Apple hardware. After years of development and effort to make Fusion support Windows on Arm _without_ explicit support, and even in the face of ambiguity in several areas, we recently released VMware Fusion 13 with improvements to specifically support Windows on Arm with Fusion on Macs with Apple silicon.
Turning rebellion into money? Social entrepreneurship as the strategic performance of systems change
1 INTRODUCTION The new groups are not concerned With what there is to be learned. They got Burton suits, huh, you think it's funny, Turning rebellion into money.1 At the turn of the millennium, social entrepreneurship—broadly understood as the innovative use and combination of resources to pursue social change or address social needs (Mair & Martí, 2006)—was seemingly poised to tear down unjust structures and replace them with more equitable systems.
Fusion 13 Pro and Player Are Here!
VMware Fusion 13: Now available for Intel and Apple Silicon Macs The time is now! After a long wait, we’re proud to announce the general availability of the VMware Fusion 13 product line: Fusion 13 Pro and Fusion 13 Player, for both Intel as well as the latest Apple Silicon Macs. After years of ongoing development and several Tech Previews, we’re ready to bring Windows 11 and more to both Intel and Apple Silicon Macs with the latest major version of VMware Fusion.
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo - Nature Communications
Abstract Targeted protein degradation offers an alternative modality to classical inhibition and holds the promise of addressing previously undruggable targets to provide novel therapeutic options for patients. Heterobifunctional molecules co-recruit a target protein and an E3 ligase, resulting in ubiquitylation and proteosome-dependent degradation of the target.
Just Released: VMware Fusion 22H2 Tech Preview
We know it’s been a long time coming, so we’re happy to be able to finally share a little of what we’ve been working on for the Mac platform. In this free, public release, we’re looking for feedback from users as we iron out kinks and add new capabilities to Fusion, on both Intel as well as Apple Silicon, in preparation for more formal support later this year.
UW Press: Fugitive Texts
Fugitive Texts Slave Narratives in Antebellum Print Culture Michaël Roy Translated by Susan Pickford Translated by Susan Pickford Antebellum slave narratives have taken pride of place in the American literary canon. Once ignored, disparaged, or simply forgotten, the autobiographical narratives of Frederick Douglass, Harriet Jacobs, and other formerly enslaved men and women are now widely read and studied. One key aspect of the genre, however, has been left unexamined: its materiality.
Fusion 12.2 Now Available
The Desktop Hypervisor team at VMware is happy to announce the release of the latest update to Fusion 12, with changes to support macOS Monterey hosts, fixes for some persistent bugs, as well as improvements to the security and management of Fusion at scale. To update, just select ‘Check for Updates’ in the VMware Fusion menu in the Menu Bar.
Announcement: VMware Fusion for Apple silicon Public Tech Preview Now Available
It is with great pride and pleasure that we announce the public availability of VMware Fusion for Apple Silicon Public Tech Preview! With more than a year in development, and a few weeks of a successful Private Tech Preview, it’s finally time for us to show the world what we’ve been working on. Download Fusion for Apple Silicon Now To deliver Fusion for Apple Silicon devices we’ve had to re-evaluate every part of the Fusion technology stack.
Fusion on Apple Silicon: Progress Update
It’s been a few months since our informal announcement via Twitter back in November where we committed to delivering VMware VMs on Apple silicon devices, so we wanted to take this opportunity to share a bit about how our progress with our little project to bring Fusion to life on Apple silicon Macs this year.
Black Friday Sale is On! - VMware Fusion Blog
It’s that time of year again! The biggest sale of the year this time around offers up to 30% discount on your favorite Desktop Hypervisor products: VMware Fusion Pro and VMware Fusion Player! Upgrades have never been cheaper, with 20% discount on top of the already reduced 2020 pricing! Upgrade from Fusion 10 or Fusion 11 ‘standard’ to Fusion 12 Player (commercial license) for only $63! (USD) Or upgrade your copy of Fusion 10 Pro or Fusion 11 Pro to the ultimate: Fusion 12 Pro for only $80!...
Fusion 12.1 Now Shipping - VMware Fusion Blog
Hot off the heels of macOS 11 Big Sur’s public release, today we’ve shipped an update to Fusion which addresses some compatibility issues, bring performance improvements, and even introduces some new features. For starters, we’ve enabled Nested / VT-X support for Macs that don’t have ‘VMCS Shadowing’ hardware features. Users can once again deploy ESXi or Windows with VBS or Hyper-V (WSL) enabled, as well as other nested Hypervisors like VMware Workstation for Linux.
Fusion 12: Now Available! - VMware Fusion Blog
Team Fusion is proud to announce the general availability of VMware Fusion 12 Pro and VMware Fusion 12 Player! Quick Links: Direct Download Fusion 12 Pro Buy Fusion 12 Pro Get Fusion 12 Player for Personal Use (Free!) VMware Desktop Hypervisor Page Evaluate VMware Fusion macOS Big Sur on macOS Big Sur To recap some of the new features we’ve brought to this release: macOS Big Sur Host and Guest Containers and Kubernetes with ‘vctl‘ and kind DirectX 11 and OpenGL 4.1 eGPU Support Monster VMs –...
Announcing: VMware Fusion 12 and Workstation 16 - VMware Fusion Blog
It is our pleasure and privilege to announce the upcoming VMware Desktop Hypervisor product lines for 2020: VMware Fusion 12, and VMware Workstation 16. (Want just the Workstation angle? Check out the Workstation 16 Blog announcement!) Quick Overview Building on over 20 years of local virtualization excellence, the latest releases of our favorite virtualization tools deliver some amazing new capabilities for IT Admins, for Developers, and for everyone else.
Ready for Testing: Updated Tech Preview with Big Sur Support - VMware Fusion Blog
At WWDC 2020, the good folks at Apple wow’d us with a look at the next major version of macOS: 11.0 Big Sur, and it’s no stretch for us to say: We’re pleasantly impressed. We’ve been working to update Fusion with support for the new rendition of macOS, and today we’re pleased to share with you some early progress with the introduction of a new Tech Preview.
Another View: Where do you stand?
Columnists increase font size The protests today are about refusing to run from the truth. Share “What if you saw her dead on the ground, how can you run when you know?” These words came back to me when I thought about the tragic death of George Floyd and the protests surrounding his death. These words are from the song “Ohio” written by Crosby, Stills, Nash and Young four short months after the killing of four student protesters by the Ohio National Guard at Kent State in 1970.
What Is the Civic University For?
Glasgow City Chambers and George Square in Glasgow, Scotland. (Photo by iStock/Susanne Neumann) As John Goddard has , “There are two key questions that each university should be able to answer. The first is: ‘what are we good at?’ And the second is ‘what are we good for?’” All universities engage with the first question by attracting the best people and giving them the space to excel.
VMware Fusion 11.5: Now With Container Support - VMware Fusion Blog
tldr; Fusion Supports Containers! Download the bits below! Download Release Notes vctl getting started guide Today is a big day for us on the Desktop Hypervisor team. Our beloved products Fusion and Workstation are getting some pretty significant updates for no extra cost to existing users.
DirectX 11 Now in Testing with VMware Fusion Tech Preview 20H2 - VMware Fusion Blog
The VMware Fusion and Workstation team is excited to announce the release of our 20H2 Technology Preview featuring the first drop of our DirectX 11 support! Quick links to the bits: Fusion Pro for Mac Direct Download Download Page Community Forum Benchmark ran with Radeon 5500M with 4GB of video ram assigned to the VM, Window was 2560×1440 on a 4K external display Provides support for DirectX 11 (Direct3D v11) and OpenGL 4.1 graphics capabilities in the guest operating systems! Obviously DX11...
Expert View on Virtual Machines: Use Cases and Future Trends
In an enterprise IT world in which everything seems to change every six months – or faster – virtual machines have had a remarkably long run. Depending on when you count the start date, VM’s have been around some 20 years. Virtual machines have remained a mainstay of enterprise IT, even as cloud computing, artificial intelligence, and many other emerging technologies have shifted the tech landscape. What’s up with virtual machines today?
How seeing the molecular machinery of the coronavirus will help scientists design a treatment
by Onisha Patel, Isabelle Lucet and Michael Roy, The Conversation Credit: National Institutes of Health In the race to develop a treatment for COVID-19, the disease threatening millions of lives around the world, scientists are studying every aspect of the SARS-CoV-2 coronavirus that causes it. One vital step is understanding the precise shape and structure of the virus at the molecular level. Knowing the shape lets scientists identify targets and design drugs to hit them.
how seeing the molecular machinery of the coronavirus will help scientists design a treatment
In the race to develop a treatment for COVID-19, the disease threatening millions of lives around the world, scientists are studying every aspect of the SARS-CoV-2 coronavirus that causes it. One vital step is understanding the precise shape and structure of the virus at the molecular level. Knowing the shape lets scientists identify targets and design drugs to hit them. This approach was used to create the anti-influenza drugs oseltamivir and zanamivir (Tamiflu and Relenza) among others.
Fighting the COVID-19 Coronavirus with VMware Fusion and Folding At Home - VMware Fusion Blog
HELP ERADICATE CORONAVIRUS COVID-19 WITH YOUR SPARE CPU CYCLES >> Quick Link to the OVA Appliance What a time to be alive. I’m writing this from my apartment in San Francisco where I’ve been sheltering in place for almost 2 weeks now.
VMware Fusion Tech Preview 20H1: Introducing Project Nautilus - VMware Fusion Blog
It’s Tech Preview time, and this year we’re doing things a bit differently. Let’s dive in! New Decade, New Approach to “Beta” Here on the Fusion team, we want to get features in the hands of customers faster than ever before, and we want to iterate and refine things with the guidance of our users, and to do so transparently, out in the open, as much as possible. In that vein, for the Fusion Pro Tech Preview 2020 we’re doing things a bit differently than we have in previous years.
Black Friday Sale is on! - VMware Fusion Blog
It’s that time of year again! The time where we offer up our biggest savings on our favorite desktop hypervisor products, VMware Fusion and VMware Workstation! Fusion 11.0 customers can install Fusion 11.5 as a free upgrade without needing a new license key, but for users still on Fusion 8 or Fusion 10, now is the best time to upgrade to the latest and most advanced releases yet! Fusion 11.5 introduces support for the latest Windows updates, as well as macOS Catalina with Sidecar support! Oh,...
Expert View on Virtual Machines
In an enterprise IT world in which everything seems to change every six months – or faster – virtual machines have had a remarkably long run. Depending on when you count the start date, VM’s have been around some 20 years. Virtual machines have remained a mainstay of enterprise IT, even as cloud computing, artificial intelligence, and many other emerging technologies have shifted the tech landscape. What’s up with virtual machines today?
Workstation 15.5 Pro and Player Available Now! - VMware Workstation Zealot
It is with great pleasure that we are able to announce the immediate availability of VMware Workstation 15.5 Pro and Player! Our major release this year comes as a free upgrade for existing version 15 customers, with upgrade discounts available for v12 and v14 customers.
VMware Fusion 11.5 Available Now! - VMware Fusion Blog
It’s with great pleasure that we announce the immediate availability of VMware Fusion 11.5! Download here! Still on Fusion 10 or 8.5? Upgrade here with 20% off!! Release notes This release comes as a free upgrade to existing Fusion 11 users, with Fusion 8.5 and v10 customers being still eligible for discount upgrade pricing. This release also extends support for v11 customers until December 2020.
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