Min-Yi Chung on Muck Rack

Min-Yi Chung

As seen in: Cell Reports
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Articles

4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay

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By Ramona Weber, Min-Yi Chung, Csilla Keskeny, Ulrike Zinnall
| Cell Reports
Highlights • 4EHP and GIGYF1/2 induce co-translational mRNA decay • Targeted transcripts are characterized by ribosome pausing and collision • mRNA decay requires ribosome pausing, DDX6, and partially ZNF598 • Identified mRNAs encode secreted and membrane-bound proteins or tubulin subunits Summary Current models of mRNA turnover indicate that cytoplasmic degradation is coupled with translation.
Open in Who Shared Issue with article?
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By Daniel Peter, Stefan Grüner, Ramona Weber, Lara Wohlbold, Min-Yi Chung, Oliver Weichenrieder, Eugene Valkov, Cátia Igreja, Elisa Izaurralde
| secure.jbs.elsevierhealth.com
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