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Eradicating fungal biofilm-based infections by ultrasound-assisted semiconductor sensitized upconversion photodynamic therapy - Nature Communications
Abstract Fungal biofilms, as self-produced extracellular polymeric substances that resist antifungal agents and immune defense, represent a major cause of treatment failure and recurrent infections. Therefore, it is of great importance to eradicate fungal biofilms to achieve efficient therapy. This study develops a synergistic reactive oxygen species (ROS)-enhanced strategy to eradicate Candida albicans biofilms by designing ultrasound-light dual-responsive nanohybrids (UCNP@CR).
Absence of neutrophils impairs the host defense in murine footpad model of chromoblastomycosis
Loading metrics Open Access Peer-reviewed Research Article Citation: Huang H, Li M, Liu Y, Chen Y, Xie Z, Luo M, et al. (2025) Absence of neutrophils impairs the host defense in murine footpad model of chromoblastomycosis. PLoS Negl Trop Dis 19(4): e0012986. https://doi.org/10.1371/journal.pntd.0012986 Editor: Angel Gonzalez, Universidad de Antioquia, COLOMBIA Received: October 8, 2024; Accepted: March 13, 2025; Published: April 23, 2025 Copyright: © 2025 Huang et al.
Grid-Scale Poverty Assessment by Integrating High-Resolution Nighttime Light and Spatial Big Data-A Case Study in the Pearl River Delta
4. Results 4.1. BDPI Results presents the results of the first, second, and third principal components and the associated BDPI. These three principal components can reveal the poverty status from different dimensions. Although the main components from the PCA may only have statistical meaning, researchers can interpret the substantive meaning of every principal component based on specialized knowledge [].
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