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Articles by Miranda Wang
Organ-specific colonization and niche remodeling in a human tissue model of metastasis
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Metastatic tumor cells must undergo multifaceted adaptation to migrate to and colonize distant organ tissues. Preclinical xenograft models fail to fully replicate the human tissue niche to interrogate this process. Here, Chramiec et al.
The USPTO Changed The Rules For Digital Design Patents – Strategic Insights On What It Means For Your Business
The USPTO issued significant new supplemental guidance (Guidance) on March 13, 2026, updating its rules for design patent protection of computer-generated icons, graphical user interfaces, and projected and holographic interface designs. The Guidance addresses a set of constraints in the prior examination framework that made design patent protection for digital interfaces burdensome and narrower in scope. The Guidance is effective immediately and applies retroactively.
The USPTO Changed the Rules for Digital Design Patents – Strategic Insights On What It Means for Your Business
The USPTO issued significant new supplemental guidance (Guidance) on March 13, 2026, updating its rules for design patent protection of computer-generated icons, graphical user interfaces, and projected and holographic interface designs. The Guidance addresses a set of constraints in the prior examination framework that made design patent protection for digital interfaces burdensome and narrower in scope. The Guidance is effective immediately and applies retroactively.
The USPTO Changed the Rules for Digital Design Patents - Strategic Insights On What It Means for Your Business
The USPTO issued significant new supplemental guidance (Guidance) on March 13, 2026, updating its rules for design patent protection of computer-generated icons, graphical user interfaces, and projected and holographic interface designs. The Guidance addresses a set of constraints in the prior examination framework that made design patent protection for digital interfaces burdensome and narrower in scope. The Guidance is effective immediately and applies retroactively.
Married conjoined twin tackles question everyone wants to know: ‘People are obsessed with sex’
Conjoined twin Carmen Andrade recently tied the knot with her husband, and nearly a year on, they’ve addressing the most common questions they’ve received. Carmen and Lupita Andrade, 25, were born in Mexico and grew up in Connecticut, US. They are joined by the torso and share a pelvis, reproductive system, a liver and a bloodstream. The sisters do not have the same heart or stomach. They each have one leg – Carmen controls the right one, Lupita the left.
Fitness influencer set Guinness World Record with this insane deadlift skill
Liu Weiqiang has broken a Guinness World record, and all he had to do was, quite literally, lift a finger. The Chinese fitness influencer deadlifted a jaw-dropping 144 kilograms with just his middle finger, breaking the previous record set by Egmond Molina, who achieved a one-finger deadlift of 138.5 kilograms in March 2024. To put 144 kilograms into perspective, that’s roughly the weight of a washer and dryer combo, a bathtub full of water, a small motorbike, or even two full kegs of beer. Yep.
Feel carsick in electric vehicles? The science behind the queasiness that can come with the ride Original
While electric vehicles are becoming increasingly popular for drivers around the world, many are realizing that they can make you more carsick than conventional petrol cars. If you’ve found yourself questioning why you feel a little queasy behind the wheel of the future, don’t worry. It’s a real thing, and you’re not the only one. According to multiple studies, there are very scientific reasons why a person may experience more motion sickness in an electric vehicle.
Dentist reveals the toothbrushing mistake nearly everyone is making Original
Brushing your teeth is an act we do daily, but it seems many of us may have been doing it wrong this whole time. Functional dentist Dr. Victoria Sampson has made some bold claims about the proper way to brush your teeth, and it’s sent the internet into a spiral. Dr. Sampson appeared on Steven Bartlett’s The Diary of a CEO podcast and claimed that you should never rinse your mouth after brushing your teeth.
Skyline LA 2025
5 As the pulsating heart of Los Angeles gears up for one of the most anticipated events, Insomniac’s Skyline Festival returns for its fourth iteration on February 15th and 16th, 2025. Set against the stunning backdrop of the Gloria Molina Grand Park, this year’s festival promises to shine a spotlight on the vibrant underground dance music scene of LA, while welcoming some of the industry’s most renowned artists.
CRSSD Fest Spring '25 Incoming...
8 Get ready, San Diego! CRSSD Festival is returning for its highly-anticipated Spring ’25 edition, and it’s shaping up to be an unforgettable weekend of electrifying performances, stunning views, and good vibes. On March 1 and 2, the Waterfront Park in San Diego will transform into a vibrant oasis to deliver a festival experience unique to CRSSD. Nestled in the heart of San Diego, Waterfront Park offers visitors a lush escape with its water fountains, green grass, and scenic walking paths.
Get Ready for Excision's Thunderdome: The Ultimate Bass Experience
8 The wait is over, headbangers! Excision’s Thunderdome is BACK and ready to shake the very foundations of Tacoma this February 7, 8, and 9, 2025. This is Excision’s biggest indoor show of 2025, so we cannot wait to see what changes in this experience Excision has lined up for this incredible 3-day festival. Although 3 day passes are now sold out, you can still get those single day passes… or else your FOMO is really going to hit for this event.
Hypertrophic cardiomyopathy-associated mutations drive stromal activation via EGFR-mediated paracrine signaling
Abstract Hypertrophic cardiomyopathy (HCM) is characterized by thickening of the left ventricular wall, diastolic dysfunction, and fibrosis, and is associated with mutations in genes encoding sarcomere proteins. While in vitro studies have used human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) to study HCM, these models have not examined the multicellular interactions involved in fibrosis.
LPGA Professional Oneda Castillo Achieves Coveted Master Professional Status
The Ladies Professional Golf Association is proud to announce that LPGA Class A Member, Oneda Castillo has become the latest LPGA Professional to attain the prestigious Master Professional Status. She is one of just two Black Master Professionals who have earned the distinction thanks to her more than 20 years as an LPGA Professional.
Minjee Lee Leads at the Blue Bay LPGA
On opening day at Jian Lake Blue Bay Golf Course, Minjee Lee led the field with a seven-under 65 in the first round of the Blue Bay LPGA. Lee, who won the 2016 edition of the Blue Bay LPGA, returns to the People’s Republic of China to etch her name in the trophy once more. Lee teed off on No. 10 alongside Rolex Rankings No. 1 Lilia Vu and Rolex Rankings No. 3 Celine Boutier.
Kim Paez Receives Exemption into Ford Championship presented by KCC
GILBERT, Ariz. (March 7, 2024) – The Ford Championship presented by KCC is proud to announce that Kim Paez from Peoria, Ariz., has received a sponsor exemption to play in the upcoming LPGA Tour event at Seville Golf and Country Club. Paez, a PGA Player Development Director for PING and a PGA Coach at Cave Creek Golf Club’s Reed West Academy, won the 2023 Southwest PGA Championship, becoming the first female winner in the event’s 66-year history.
Geometry and Length Control of 3D Engineered Heart Tissues Using Direct Laser Writing
Geometry and Length Control of 3D Engineered Heart Tissues Using Direct Laser Writing Geometry and mechanical characteristics of the surrounding environment affect the structure and function of engineered heart tissues (EHT). Here, we employed a 3D tissue culture platform fabricated using two-photon direct laser writing to control geometric parameters that are relevant to EHT maturation with a high degree of accuracy.
Epson Tour Winner Miranda Wang Musters Up a 66 on Day One of Blue Bay LPGA
Epson Tour winner Miranda Wang is in the mix early at the Blue Bay LPGA, carding an impressive 6-under 66 on Thursday at the Jian Lake Blue Bay Golf Course to sit in a tie for second and one shot back of major champion Minjee Lee. After parring her first two holes, the People’s Republic of China native got things rolling with a birdie on the par-5 3rd hole, quickly grabbing another on the par-4 6th hole to get to 2-under overall.
What Does The Future Hold For China’s Biopharma Industry
Magazine Article | June 1, 2022 Source: Life Science Leader By Bruce Liu, Miranda Wang, and Selene Peng Chinese biopharma stock prices have been on a roller-coaster ride, with some composites reaching historical highs in June 2021, but heading south ever since. In this article, we deep-dive into what enabled this sudden rise and examine whether the future of China’s biopharma industry looks as bleak as the stock market suggests.
China: New Trademark Law Will Come Into Effect on Nov. 1, 2019 | JD Supra
Updated: May 25, 2018: JD Supra is a legal publishing service that connects experts and their content with broader audiences of professionals, journalists and associations.
The influence of microRNAs and poly(A) tail length on endogenous mRNA-protein complexes
Despite often being depicted as long, naked molecules, messenger RNAs (mRNAs) in the cell are bound by a host of factors to form mRNA–protein complexes (mRNPs) [1–4]. In humans, hundreds of RNA-binding proteins (RBPs) have been identified, and, speaking to the complexity of mRNP complexes, many RBPs can bind the same transcript simultaneously [5, 6]. Some factors recognize specific motifs, often in 3? untranslated regions (3?
Can bacteria eat up the plastic pollution problem?
In high school, two smart women discovered a new bacteria in a local river that specifically eats phthalates, a harmful plasticizer that never degrades. Since then, Miranda Wang and Jeanny Yao have turned their discovery of plastic-eating bacteria into an innovative, award-winning business called BioCellection.
Two young scientists break down plastics with bacteria
Once it's created, plastic (almost) never dies. While in 12th grade Miranda Wang and Jeanny Yao went in search of a new bacteria to biodegrade plastic — specifically by breaking down phthalates, a harmful plasticizer. They found an answer surprisingly close to home. This talk was presented at an official TED conference, and was featured by our editors on the home page.
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