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Muhammad R Haque on Muck Rack

Muhammad R Haque

As seen in: BioRxiv
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Articles

🎨 Library Card Design Competition

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By Muhammad R Haque
| ourhubsbd.london
Calling all young artists aged 6 to 12! Design the next official Barking & Dagenham Library card based on one of two exciting themes: The Heritage of Barking & Dagenham The Future of Barking & Dagenham Libraries The winning design will be professionally printed and used as the borough’s library card. Deadline: Friday, 31 October 2025. Submit your artwork to: Universal.External@lbbd.gov.uk Brief Details: Open to children aged 6 to 12.
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TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo

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By Mariluz Araínga, Jinhee Kime, Deepanwita Bose, Muhammad R Haque
| BioRxiv
Abstract HIV-1 persistence during ART is due to the establishment of long-lived viral reservoirs in resting immune cells. Using an NHP model of barcoded SIVmac239 intravenous infection and therapeutic dosing of the anti-TGFBR1 inhibitor galunisertib (LY2157299), we confirmed the latency reversal properties of in vivo TGF-β blockade, decreased viral reservoirs and stimulated immune responses. Eight SIV-infected macaques on suppressive ART were treated with 4 2-week cycles of galunisertib.
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