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Muhammad S. Shamim

As seen in: Nature, The Cureus Journal of Medical Science
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Articles

An encyclopedia of human enhancer–gene regulatory interactions

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By Andreas R. Gschwind, Kristy S. Mualim, Alireza Karbalayghareh, Maya U. Sheth, Kushal Dey, Evelyn Jagoda, Ramil Nurtdinov, Wang Xi, Anthony Tan, Hank Jones, X. Rosa Ma, David Yao, Dulguun Amgalan, Judhajeet Ray, Chad Munger, Joseph Nasser, Ziga Avsec, Benjamin James, Muhammad S. Shamim, Neva C. Durand, Suhas S. P. Rao, Benjamin Doughty, Kalina Andreeva, Jacob C. Ulirsch, Kaili Fan, Elizabeth Perez, Elizabeth Pérez, Tri C. Nguyen, Trí Nguyễn, David Kelley, Hilary Finucane, Jill Moore, Zhiping Weng, Manolis Kellis, Michael Bassik, Berk Ustun, Alkes L Price, Michael Beer, Roderic Guigó, John A. Stamatoyannopoulos, Erez Lieberman Aiden, William J. Greenleaf, Christina Leslie, Lars M. Steinmetz, Anshul Kundaje, Jesse M. Engreitz, James Galante, Ragini Mahajan
| Nature Verified
Abstract Identifying transcriptional enhancers and their target genes is essential for understanding gene regulation and the effect of human genetic variation on disease1,2,3,4,5,6. Here we create and evaluate a resource of more than 92 million enhancer–gene regulatory interactions across 1,458 biosamples covering 369 cell types and tissues, by integrating predictive models, chromatin states, three-dimensional contacts and large-scale genetic perturbations generated by the ENCODE Consortium7.
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Enhancing Surgical Curriculum: Trainees' Perspectives on Laparoscopic Simulation and Assessment

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By Jitendra Singh, Muhammad S. Shamim, Yousif Aawsaj
| The Cureus Journal of Medical Science
Specialty Please choose I'm not a medical professional. Allergy and Immunology Anatomy Anesthesiology Biostatistics Cardiac/Thoracic/Vascular Surgery Cardiology Critical Care Dentistry Dermatology Diabetes and Endocrinology Emergency Medicine Epidemiology and Public Health Family Medicine Forensic Medicine Gastroenterology General Practice Genetics Geriatrics Health Policy Hematology HIV/AIDS Hospital-based Medicine I'm not a medical professional.
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