Muya Shu on Muck Rack

Muya Shu

As seen in: Royal Society of Chemistry, Cell Press
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Articles

Embryo spatial 3D genomics

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By Bo Gou, Yuetong Xu, Muya Shu, Yuang Ma
| biorxiv.org
Abstract The 3D architecture of the genome is crucial for controlling gene expression and organ development. Here, we introduce a spatial 3D genomics approach for assessing chromatin conformation in-situ in tissue sections, by integrating microfluidic deterministic barcoding and SPRITE procedures. This method was applied to mouse embryo sections, revealing a hierarchical model of chromatin interactions within and between compartments in various organs.
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Single-cell chromatin accessibility identifies enhancer networks driving gene expression during spinal cord development in mouse

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By Muya Shu, Danni Hong, Hongli Lin
| Cell Press Verified
Ybot-Gonzalez P. Gaston-Massuet C. Girdler G. Klingensmith J. Arkell R. Greene N.D.E. Copp A.J. Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling. Development. 2007; 134: 3203-3211https://doi.org/10.1242/dev.008177 Liem K.F. Jessell T.M. Briscoe J. Regulation of the neural patterning activity of sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites. Development. 2000; 127: 4855-4866 Mizutani C.M. Meyer N. Roelink H. Bier E.
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Complexity of enhancer networks predicts cell identity and disease genes revealed by single-cell multi-omics analysis

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By Hongli Lin, Lifang Liu, Muya Shu, Danni Hong
| biorxiv.org
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