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Muzaddid Sarker on Muck Rack

Muzaddid Sarker

As seen in: PLOS ONE, Cell Press
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Articles

Strategies for the production of isotopically labelled Fab fragments of therapeutic antibodies in Komagataella phaffii (Pichia pastoris) and Escherichia coli for NMR studies

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By Donald Gagné, Muzaddid Sarker, Genevieve Gingras, Derek Hodgson
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Gagné D, Sarker M, Gingras G, Hodgson DJ, Frahm G, Creskey M, et al. (2023) Strategies for the production of isotopically labelled Fab fragments of therapeutic antibodies in Komagataella phaffii (Pichia pastoris) and Escherichia coli for NMR studies. PLoS ONE 18(11): e0294406.
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Distinct Binding Modes of Vinculin Isoforms Underlie Their Functional Differences

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By Andrey Krokhotin, Muzaddid Sarker, Ernesto Alva Sevilla, Lindsey M. Costantini
| Cell Press Verified
Highlights • The Vt and MVt C-terminal hairpin forms direct interactions with the F-actin surface • The MVt C terminus is not essential for inhibition of Vt-mediated actin bundling • Deletion of MVt H1 helix converts actin reorganization properties of MVt to Vt Summary Vinculin and its splice isoform metavinculin play key roles in regulating cellular morphology, motility, and force transduction. Vinculin is distinct from metavinculin in its ability to bundle filamentous actin (F-actin).
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