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Myeung-Ryun Seo on Muck Rack

Myeung-Ryun Seo

As seen in: Nature
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Articles

Combination strategy of photothermal therapy and targeted IFN-β mutein priming elicits a durable abscopal effect

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By Jinwon Park, Ho Jin Lee, Jieun Park, Sungyoul Hong, Kyoung Doo Song, Naoto T Ueno, Jangsoon Lee, Yoon-La Choi, Mi Jeong Kwon, Yu-Kyoung Oh, Myeung-Ryun Seo, Hee Geon Park, Hobin Yang, Joon-Seok Choi
| Nature Verified
Abstract Metastatic tumors remain difficult to cure due to frequent dissemination and recurrence. While photothermal therapy (PTT) can trigger abscopal effects, PTT monotherapy often fails to sustain systemic immunity. Here, we investigated a tripartite strategy combining PTT, a tumor-targeted type I interferon immunocytokine, and immune checkpoint blockade.
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