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Myriam Baratin on Muck Rack

Myriam Baratin

As seen in: Cell Press
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Articles

Lymphatic Endothelial Cells Are Essential Components of the Subcapsular Sinus Macrophage Niche

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By Isabelle Mondor, Aix Marseille Univ, Myriam Baratin, Marine Lagueyrie
| Cell Press Verified
Angeli V. Ginhoux F. Llodrà J. Quemeneur L. Frenette P.S. Skobe M. Jessberger R. Merad M. Randolph G.J. B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity. 2006; 24: 203-215 Bain C.C. Bravo-Blas A. Scott C.L. Perdiguero E.G. Geissmann F. Henri S. Malissen B. Osborne L.C. Artis D. Mowat A.M. Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice. Nat. Immunol. 2014; 15: 929-937 Baratin M. Simon L. Jorquera A.
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T Cell Zone Resident Macrophages Silently Dispose of Apoptotic Cells in the Lymph Node

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By Myriam Baratin, Aix Marseille Univ, Léa Simon, Audrey Jorquera
| Cell Press Verified
In lymph nodes (LNs), dendritic cells (DCs) are thought to dispose of apoptotic cells, a function pertaining to macrophages in other tissues. We found that a population of CX3CR1+ MERTK+ cells located in the T cell zone of LNs, previously identified as DCs, are efferocytic macrophages. Lineage-tracing experiments and shield chimeras indicated that these T zone macrophages (TZM) are long-lived macrophages seeded in utero and slowly replaced by blood monocytes after birth.
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