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Myung Ah Lee

As seen in: Nature, MDPI
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Articles

A phase II study of alpelisib and capecitabine in patients with previously treated metastatic colorectal cancer (KCSG-CO21-04)

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By Ah Reum Lim, Seok Yun Kang, Moon Ki Choi, Myung Ah Lee, Jin Kim, Dong-Hoe Koo, Seung-Hoon Beom, Soojung Hong, Jungmin Jo, Jwa Hoon Kim, Soohyeon Lee
| Nature Verified
Abstract This open-label, single-arm, multi-center phase II study investigated the clinical activity and safety of alpelisib in combination with capecitabine in patients with PIK3CA-mutant metastatic colorectal cancer who had progressed after standard chemotherapy. Patients received oral alpelisib and capecitabine in 21-day cycles, and clinical outcomes and circulating tumor DNA were longitudinally assessed. A total of 26 patients were enrolled across nine institutions.
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Exploring the efficacy of fluorouracil and platinum based chemotherapy in advanced hepatocellular carcinoma to bridge the treatment gap in resource limited settings | Scientific Reports

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By Kabsoo Shin, In-Ho Kim, Myung Ah Lee
| Nature Verified
Abstract Advanced hepatocellular carcinoma (HCC) poses treatment challenges, especially where access to multi-kinase inhibitors and ICIs is limited by high costs and lack of insurance. This study evaluates the effectiveness of 5-fluorouracil (5-FU) plus platinum-based chemotherapy as an alternative systemic treatment for advanced HCC. A retrospective analysis of advanced HCC patients treated with 5-FU plus platinum-based chemotherapy was conducted.
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Early Increase in Circulating PD-1+CD8+ T Cells Predicts Favorable Survival in Patients with Advanced Gastric Cancer Receiving Chemotherapy

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By Hyunho Kim, Kabsoo Shin, Joori Kim, Myung Ah Lee
| MDPI
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