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Articles by Na Wu
Ice–water interfaces drive speciation transformation and suppress bioavailability potential of freshly deposited arsenic during soil freeze–thaw cycles
Abstract Ubiquitous freeze–thaw cycles serve as a hidden driver reshaping arsenic (As) bioavailability in industrial and adjacent agricultural soils impacted by industrial emissions. Here we show that ice–water interfaces trigger rapid changes in the speciation and bioavailability potential of freshly deposited As particles in soils, primarily within the first three freeze–thaw cycles.
Nanofibrous aerogels with continuous conductivity gradient for ultrabroadband absorption-dominant electromagnetic interference shielding
Abstract Electromagnetic interference (EMI) shields are limited by a severe impedance mismatch with free space, leading to strong reflections and secondary radiation. Here, we introduce ultralight all-polymer aerogels featuring a continuous through-thickness conductivity gradient (MCAs), fabricated in a single step via diffusion-driven oxidative polymerization of pyrrole within aramid nanofiber scaffolds.
Familial short stature: genetic architecture, risk stratification, and precision management
Abstract Background: Familial short stature (FSS) has traditionally been considered a benign growth pattern characterized by short stature clustering within families and has often been regarded as a normal variant of growth. However, recent advances in genomic technologies have demonstrated that a subset of children presenting with an FSS phenotype harbor identifiable monogenic variants, particularly in genes involved in growth plate development and skeletal growth.
Robust MXene‑Based Electromagnetic Shielding Textiles Integrated Smart Switching and Tri‑Mode Thermal Conversion
Bin Li and Meng Wei contributed equally to this work. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description smll74942-sup-0001-SuppMat.docx10.3 MB Supporting File: smll74942-sup-0001-SuppMat.docx.
State-dependent reconfiguration failure of the basal forebrain-cortical gradient in Parkinson’s disease with freezing of gait
Abstract Accumulating evidence implicates cholinergic dysfunction in freezing of gait (FOG) in Parkinson’s disease (PD). Given the basal forebrain (BF) provides the primary cholinergic input to the cortex, elucidating BF-cortical connectivity and its dynamic reconfiguration during motor challenges in PD-FOG is important. This study included 44 PD-FOG, 45 without FOG (PD-NFOG), and 27 healthy controls (HC). All underwent diffusion and resting-state functional MRI.
Continuous-Conductivity-Gradient All-Organic Aerogels with Machine-Learning-Assisted Design toward Ultrabroadband, Ultralow-Reflection Electromagnetic Shielding
Yue Liu and Na Wu contributed equally to this work. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adma74414-sup-0001-SuppMat.docx6.4 MB Supporting File 1: adma74414-sup-0001-SuppMat.docx.
Historical Biogeography and Climate-Driven Vulnerability of Torrent Frogs (Ranidae: Amolops ): Insights Into Long-Term Climate Refugia
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The mtDNA sequence data are available on GenBank under accession numbers PX500320-PX500649 (COI), PX499874-PX500203 (16S rRNA), PX577668-PX577997 (ND2). R code used in this study was available on Dryad: https://doi.org/10.5061/dryad.r2280gbs2. A reviewer access link is provided here: http://datadryad.org/share/LINK_NOT_FOR_PUBLICATION/t5WIvSLNiz2ADQ7yI2kSMbamGUksdgcBv7naziKlZzk.
Exploring the sustainable development of regional culture by tourist souvenir design—development and application of Pingyao lacquerware tourism souvenir model
Abstract Despite the rapid growth of cultural tourism making souvenirs an increasingly important medium for disseminating regional culture, Pingyao lacquerware souvenirs generally lack distinct regional characteristics and insufficient cultural expression. The primary reason is the scarcity of professional designers in this field, with production relying on craftsmen who lack systematic training.
A highly efficient detection model for early-stage Parkinson’s disease using non-contact, multi-modality measurement and artificial intelligence
Abstract Early diagnosis of Parkinson’s disease (PD) is challenging due to the difficulty in identification of various early motor signs. We aimed to develop and validate a highly efficient detection model for early-stage PD using an optimal modality (OM) selection strategy. 151 off-medication, early-stage PD patients and 138 controls were divided into a development cohort and a validation cohort at 5:1 ratio.
Diagnostic accuracy and clinical performance of deep learning models for grading diabetic retinopathy: a systematic review and meta-analysis
Abstract Background: Diabetic retinopathy (DR) is a leading cause of preventable visual impairment worldwide, and its precise severity grading is critical for optimizing clinical management. Conventional frameworks, notably the International Clinical Diabetic Retinopathy (ICDR) scale, are often hindered by substantial inter-observer variability and high dependency on specialist expertise.
Bimodal ultrasound assessment of cerebral hemodynamics in preterm infants stratified by maternal immunotherapy: implications for early prediction of intraventricular hemorrhage
Abstract Objective: To evaluate the clinical value of bedside bimodal ultrasound in assessing early cerebral circulation in preterm infants from structural and functional perspectives, and to examine whether maternal recurrent spontaneous abortion (RSA), maternal active immunotherapy status, and ultrasound-derived markers were associated with neonatal cerebral hemodynamic trajectories and clinically significant intraventricular hemorrhage (IVH).
Energy-Efficiency-Dried Silver Nanowire Aerogels With Orientational-Tunable Gigahertz and Terahertz Electromagnetic-Interference Shielding
1 Introduction The relentless pursuit of higher data transport rates and novel sensing capabilities is pushing wireless technologies into higher spectral territories [1, 2]. Spanning from gigahertz (GHz) to terahertz (THz) frequencies, this expansion is foundational for sixth-generation (6G) communications and next-generation high-resolution imaging, creating an urgent demand for materials with broadband, tunable electromagnetic interference (EMI) shielding [3, 4].
Resilient Recursive Filtering for Integrated Electricity-Gas Systems under Uncertain Communication Links
Wu, N., Wang, C., Li, G., Bai, X. and Liu, J. (2026), Resilient Recursive Filtering for Integrated Electricity-Gas Systems under Uncertain Communication Links. IEEJ Trans Elec Electron Eng. https://doi.org/10.1002/tee.70370 References 1, , , , . Robust control for renewable-integrated power networks considering input bound constraints and worst case uncertainty measure. IEEE Transactions on Control of Network Systems 2019; 6(3): 1210–1222. 2, , .
Multidimensional Pathogen Fingerprinting via DNA Scaffold-Confined Enzymatic Synthesis of Silicon Quantum Dots Click to copy article link Article link copied!
Abstract Click to copy section linkSection link copied! Accurate and highly sensitive detection of pathogenic bacteria is essential to public health. Conventional biosensors often rely on bulk signal amplification, which suffers from diffusion-limited kinetics and high background signals.
Intermittent Theta-Burst Stimulation for Depressive Symptoms in Parkinson Disease : A Randomized Clinical Trial
Supplement 1. Trial Protocol and Statistical Analysis Plan Supplement 2. eTable 1. MNI Coordinates for All Channels and Corresponding Brodmann Area Mappings eTable 2. Raw Data of Primary and Secondary Outcomes eTable 3. Summary Statistics and Results From Mixed Model Analysis of Change in Outcomes From Baseline, by Visit eTable 4. Sensitivity Analysis of the Primary End Point: Changes in HAMD-24 From Baseline to Week 6 eTable 5. Statistics of AUC of HbO in the DLPFC-L, FPA-L and FEF-L eFigure 2.
Nitrate-Driven Proton-Coupled Photoelectron Transfer Enables Cascade C–N Coupling of Lactic Acid to Alanine Click to copy article link Article link copied!
Abstract Click to copy section linkSection link copied! The sustainable synthesis of amino acids from waste-derived feedstocks remains challenged by high energy input, costly nitrogen source, and inefficient C–N formation efficiency of conventional bio-, thermo-, and photocatalytic routes.
The influence of stress path and flaw morphology on the failure mechanism and mechanical properties of rock masses
Loading metrics Open Access Peer-reviewed Research Article Citation: Wu N, Gan Y, Hu J, Sun R, Zeng H (2026) The influence of stress path and flaw morphology on the failure mechanism and mechanical properties of rock masses. PLoS One 21(5): e0349190. https://doi.org/10.1371/journal.pone.0349190 Editor: Dajiang Geng, China Construction Fourth Engineering Division Corp. Ltd, CHINA Received: February 15, 2026; Accepted: April 26, 2026; Published: May 14, 2026 Copyright: © 2026 Wu et al.
Comparison of 1.1-mm and 1.7-mm Probes in Transbronchial Mediastinal Cryobiopsy: A Randomized Trial
Introduction Recent studies have shown that combined use of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and cryobiopsy provides a higher diagnostic yield for mediastinal lesions as compared with EBUS-TBNA alone. Currently, cryoprobes with diameters of 1.1 mm and 1.7 mm have been reported to be used for mediastinal cryobiopsy.
Hypoperfusion Intensity Ratio is Correlated With the Risk of Futile Reperfusion After Endovascular Treatment
ABBREVIATIONS FR (futile reperfusion) EVT (endovascular treatment) HIR (hypoperfusion intensity ratio) TLC (tissue-level collaterals) sICH (symptomatic intracranial hemorrhage) OR (odds ratio) CI (confidential interval) AIS (acute ischemic stroke) LVO (large vessel occlusion) RESTORE (REperfusion therapy for acute ischemic STrOke due to large aRtEry occlusion) CTA (computed tomography angiography) CTP (computed tomography perfusion) MRA (magnetic resonance angiography) PWI (perfusion weighted...
METTL14 Aggravates Sepsis‐Induced Acute Kidney Injury by Promoting Ferroptosis Through m6A Modification of BMAL1
1 Introduction Sepsis denotes a systemic, life-endangering disorder marked by the dysfunction of multiple organs. Its pathogenesis primarily involves excessive generation of reactive oxygen species (ROS) [1]. Among patients diagnosed with sepsis, around 60% experience the onset of acute kidney injury (AKI) [2, 3]. Patients with sepsis who develop concurrent AKI exhibit a mortality rate 2–3 times greater than those with sepsis alone [4, 5].
Extreme heat and stock market participation: Evidence from China
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Hybrid female sterility due to cohesin protection errors in mouse oocytes
Abstract Hybrid incompatibility can lead to lethality and sterility of F1 hybrids, promoting speciation. The cell biological basis underlying hybrid incompatibility remains largely unknown, especially in mammals. Here, we found that female hybrids between Mus musculus domesticus and Mus spicilegus mice are sterile due to the failure of homologous-chromosome separation in oocyte meiosis, producing aneuploid eggs.
Oriented cell divisions induce basal progenitors and regulate neural expansion across tissues and species
Abstract Nervous system expansion relies on progenitor proliferation, yet its regional and evolutionary regulation is incompletely understood. While basally dividing progenitors are implicated in neocortical growth, their developmental origins and relevance beyond the cortex remain unclear. We show here that double inactivation of spindle orientation regulators GPSM2 and SAPCD2 in mice completely reorients progenitor divisions in both the neocortex and retina.
Noninvasive photoacoustic computed mesoscopy for longitudinal brain imaging
Abstract Photoacoustic imaging has become a powerful tool for visualizing the brain morphology, function, and metabolism. However, severe optical scattering and high-frequency acoustic attenuation within the brain degrade the performance of photoacoustic brain imaging. To address such limitation, we propose a line scanning–based photoacoustic computed mesoscopic (PACMes) approach for noninvasive, high-resolution, and longitudinal visualization of cerebral vasculature inside the intact mouse brain.
Overcoming host restrictions to enable continuous passaging of GII.3 human norovirus in human intestinal enteroids
Abstract The establishment of human intestinal enteroids (HIEs) as a model for human norovirus (HuNoV) replication has been transformative for studying this leading cause of gastroenteritis. However, indefinite passaging of HuNoVs in HIEs remained a challenge, necessitating the use of patient stool samples as viral inocula. Using RNA-seq, we identified CXCL10, CXCL11, and CCL5 as up-regulated chemokines, suggesting their potential as host restriction factors.
Observation of super-ballistic Brownian motion in liquid
Abstract Brownian motion is a foundational physical process characterized by a mean squared displacement that scales linearly in time in thermal equilibrium, known as diffusion. At short times, the mean squared displacement becomes ballistic, scaling as t2. This effect was predicted by Einstein in 1907 and recently observed experimentally.
Complex perishable technologies from the North American Great Basin reveal specialized Late Pleistocene adaptations
Abstract Structurally and functionally complex technologies were a defining element of Late Pleistocene societies, but physical examples of them remain extremely rare in the archaeological record because most were made from perishable raw materials. The sparse material record of those myriad technologies limits our ability to formulate nuanced models about this critical period in human history.
Hydrostatic pressure induces strong leakage of dissolved organic matter from “marine snow” particles
Abstract Marine snow forms at the ocean surface, sinks to depth, and ultimately enables carbon sequestration in the seabed. Fast-sinking marine snow particles, such as diatom aggregates, encounter a rapid increase in hydrostatic pressure during their descent.
School discipline disparities increase when neighborhood Black population changes
Abstract The racial landscape of US neighborhoods shifted tremendously over the past decade, raising questions about how these changes are reflected in local schools. This study combines school zone shapefiles with census and Civil Rights Database data to explore whether neighborhood racial change in Black populations predicts changes in Black-white school suspension disparities from 2010 to 2018.
In vivo functional profiling and structural characterization of the human GLP1R A316T variant
Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are effective therapies for type 2 diabetes (T2D) and obesity, yet patient responses are variable, with GLP1R gene variation potentially linked to therapeutic outcomes. A GLP1R natural missense variant, A316T, protects against T2D and cardiovascular disease. Here, we generated and characterized a human GLP1R A316T mouse model.
Nanocollision promotes locomotion of dendritic cells for tumor therapy
Abstract Mechanical stimuli originating from extracellular matrix have been proved to affect antitumor immunity by regulating dendritic cell (DC) locomotion. However, the immunological consequences of ultrasmall bioparticle–induced nanocollision remain largely an unexplored realm despite its ubiquitous and incessant occurrence within the in vivo milieu.
Single-molecule localization microscopy reveals the molecular organization of endogenous membrane receptors
Abstract Super-resolution microscopy in combination with genetic labeling methods allows imaging of single proteins in cells. However, visualizing endogenous proteins on primary cells remains challenging due to the use of sterically demanding antibodies for labeling. Here, we demonstrate how immunolabeling conditions and antibody cross-linking influence the quantification and identification of membrane receptor stoichiometry on cells using single-molecule localization microscopy.
The ocean’s biological carbon pump under pressure
Abstract Increasing hydrostatic pressure induces the release of dissolved organic matter from rapidly settling marine particles and contributes to the depth attenuation of carbon fluxes. SIGN UP FOR THE AWARD-WINNING SCIENCEADVISER NEWSLETTER The latest news, commentary, and research, free to your inbox daily The ocean is a major sink of carbon and governs atmospheric carbon dioxide levels on timescales of tens to thousands of years.
Electrolyte design for aqueous batteries
Abstract Aqueous batteries, with their inherent safety, operational simplicity, and cost-effectiveness, have emerged as promising candidates for grid-scale energy storage applications. However, the relatively low output voltage of aqueous systems continues to limit their achievable energy density.
High-efficiency methane consumption by atmospheric methanotrophs in subsurface karst caves: The irrefutable methane sink
Abstract Subsurface karst systems represent substantial but underexplored methane sinks, yet the identities and activities of cave-dwelling methanotrophs remain poorly characterized. We detected increased methane oxidation rates from 2.9 ± 0.1 to 90.7 ± 4.5 ng·g−1·hour−1 while supplied with 2 to 500 parts per million (ppm) CH4 to cave sediments.
Fungal infection drives metabolic reprogramming in epithelial cells via aerobic glycolysis and an alternative TCA cycle shunt
Abstract Candida albicans–induced immunometabolic changes drive complex responses in immune cells. However, whether and how C. albicans causes remodeling of oral epithelial cell (OEC) metabolism is unclear. Here, we use in vitro experiments and patient biopsies to demonstrate that OECs undergo metabolic reprogramming when infected by C. albicans independently of candidalysin secretion, increasing glycolysis and decreasing tricarboxylic acid (TCA) cycle activity.
Discovery and preclinical evaluation of monoclonal antibodies and bispecific engagers targeting the NKG2A inhibitory receptor
Abstract NK and T cells are key effectors that eliminate cancer cells, but upregulation of the inhibitory receptor NKG2A on these cells attenuates antitumor immune responses. To counteract NKG2A inhibitory signaling, we identified two specific fully human monoclonal anti-NKG2A antibodies that block HLA-E ligand binding. These antibodies activated NK cells and enhanced antibody-dependent cellular cytotoxicity of tumor-targeting IgG1s both in vitro and in vivo.
OsRNS4-mediated cross-kingdom RNA interference is inhibited by Ustilaginoidea virens effector SCRE2 to promote infection in rice
Abstract The Ustilaginoidea virens effector SCRE2 has been previously identified to be an essential virulence factor. To elucidate molecular mechanisms underlying SCRE2 virulence function, we identify that SCRE2 interacts with Oryza sativa S-like ribonuclease family member OsRNS4. As a catalytically inactive RNase, OsRNS4 positively regulates rice immunity, depending on its RNA binding ability. OsRNS4 is unconventionally secreted through tetraspanin-positive extracellular vesicles (EVs).
Optoacoustically augmented magnetic guidewire for radiation-free minimally invasive therapies
Abstract Endovascular interventions are essential for treating cerebrovascular diseases, yet their monitoring methods commonly rely on ionizing radiation and contrast agents, posing unnecessary risks to patients and clinicians. We present a multifunctional optoacoustically augmented magnetic guidewire (OptoMaG) that integrates optoacoustic imaging with magnetic navigation to enable radiation-free, image-guided interventions.
Day-to-day fluctuations in cognitive precision predict the domain-general intention-behavior gap
Abstract The idea that better cognitive functioning helps to close the gap between goals and behavior seems self-evident, yet empirical work has found unusually weak interindividual associations between cognitive task performance and real-world, goal-relevant outcomes. Here, we resolve this paradox by shifting from trait-level to state-level analysis.
Injury-induced electrochemical coupling triggers organ growth
Abstract Organ injury triggers nonneuronal electric currents essential for regeneration. However, the mechanisms by which electrical signals are generated, sensed, and transmitted upon damage to promote organ growth remain unclear. Here, we uncover that organ repair relies on dynamic electrochemical coupling between membrane potential depolarization and intracellular signaling, essential to activate cell proliferation.
Photoinduced femtosecond spin-flip assisted by a single-mode linear phonon
Abstract Optical manipulation of spin-flip on a picosecond to femtosecond timescale has long been pursued to innovate next-generation electronic devices. However, understanding the ultrafast spin-electron-lattice coupled dynamics remains challenging, especially when the system is driven far from equilibrium. Here, we demonstrate an ultrafast light-induced spin-flip within 300 fs in Fe3GeTe2, a prototypical two-dimensional itinerant ferromagnet.
Volcanism-induced collapse and recovery of the Atlantic meridional overturning circulation under glacial conditions
Abstract Volcanic eruptions have considerable impacts on climate across various timescales; however, it remains uncertain if, and how, volcanic activity could drive climate change over multiple millennia. Here we incorporate realistic volcanic forcing into a large ensemble of glacial era–coupled atmosphere-ocean model simulations. These simulations are constrained by sulfate records from ice cores, which help estimate the timing of past major eruptions.
Hydrophobic Interaction‐Directed Solvent‐Free Ambient‐Pressure‐Dried MXene Aerogels
Conflicts of Interest The authors declare that they have no competing interests. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon request.
Left Ventricular Myxoma-Caused Recurrent Stroke in a Middle-Aged Woman: A Case Report
Back to Journals » International Medical Case Reports Journal » Volume 19 Authors Wu N, Du Y, Li X, Hu L, Li H, Gao A, Dong J, Liu L Received 13 December 2025 Accepted for publication 19 March 2026 Published 24 March 2026 Volume 2026:19 Pages 1—6 DOI https://doi.org/10.2147/IMCRJ.S587217 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Thomas E Hutson Na Wu,1 Yinuo Du,1 Xianzheng Li,2 Liting Hu,1 Huhu Li,1...
Eosinophilic heart disease | IJGM
Back to Journals » International Journal of General Medicine » Volume 19 Authors Dong J, Fu H, Wu N, Hu L, Du Y, Li H, Liu L Received 7 December 2025 Accepted for publication 25 February 2026 Published 5 March 2026 Volume 2026:19 586348 DOI https://doi.org/10.2147/IJGM.S586348 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Redoy Ranjan Jing Dong,* Haoran Fu,* Na Wu, Liting Hu, Yinuo Du, Huhu Li, Li Liu...
SpectroSwinFusion: Multi-Scale Time-Frequency Transformer with Adaptive Spatiotemporal Fusion for fault diagnosis
ABSTRACT Fault diagnosis remains a critical research focus for industrial equipment. However, the performance of existing fault diagnosis methods faces the dual challenges of data imbalance and large parameter volumes. To address this, this paper proposes a novel method named the Multi-Scale Time-Frequency Transformer with Adaptive Spatiotemporal Fusion (SpectroSwinFusion).
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