Nabarun Roy
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Molecular basis of diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptor C3aR
Abstract The complement anaphylatoxin receptor, C3aR, is a prototypical G protein-coupled receptor (GPCR) that plays multi-faceted roles in immune regulation, pro-inflammatory responses, neuroimmune modulation, and host defense mechanisms against pathogens.
Molecular mechanisms of naturally encoded signaling bias at the complement anaphylatoxin receptors
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Keywords GPCRs β-arrestins anaphylatoxin receptors complement cascade biased signaling Get full text access Log in, subscribe or purchase for full access. References 1. Lorente, J.S. ∙ Sokolov, A.V. ∙ Ferguson, G. ... GPCR drug discovery: new agents, targets and indications Nat. Rev. Drug Discov. 2025; 24:458-479 2. Hauser, A.S. ∙ Attwood, M.M. ∙ Rask-Andersen, M. ... Trends in GPCR drug discovery: new agents, targets and indications Nat. Rev. Drug Discov. 2017; 16:829-842 3. Kenakin, T. ∙ Christopoulos, A.
By Divyanshu tiwari, Kazuhiro Sawada, Annu Dalal, Sudha Mishra, Xaria X. Li, Joshua Dent, Kiae Kim, Manish Yadav, Nabarun Roy, Manisankar Ganguly, Nilanjana Banerjee, Tomasz Maciej Stepniewski, Donghoon Ahn, Kohei Yamaguchi, Hidetaka S. Oshima, Kana Hashimoto, Jenny Fung, Titaya Lerskiatiphanich, Cedric S. Cui, John Lee, Jana Selent, Asuka Inoue, Richard Clark, Ramanuj Banerjee, Fumiya Sano, Trent M Woodruff, Osamu Nureki, Arun Shukla
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Cell Press
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Opinion: India’s new security doctrine - The salience of risk-taking
Published Date - 4 June 2025, 12:19 AM By Nabarun Roy In the final hours of the India-Pakistan face-off in the second week of May, India announced that going forward, acts of terrorism directed at it would be construed as acts of war and that India would respond accordingly. From India’s point of view, the gloves are well and truly off.
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