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Nai-Jung Chiang on Muck Rack

Nai-Jung Chiang

As seen in: Nature, MDPI, The BMJ, BMC Cancer, Royal Society of Chemistry, The Lancet, European Journal of Cancer
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Articles

ACSL6 modulates docosahexaenoic acid-induced cytotoxicity to potentiate chemotherapy response in colorectal and breast cancer - Oncogenesis

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By Chi-Che Hsieh, Chun-Chun Li, Sheng-Wei Feng, Nai-Jung Chiang, Che-Hung Shen
| Nature Verified
Abstract Docosahexaenoic acid (DHA), an omega-3 polyunsaturated fatty acid, exhibits anticancer properties by modulating cell membrane composition, inducing oxidative stress, and triggering ferroptosis. Acyl-CoA synthetase long chain family member 6 (ACSL6) catalyzes DHA activation, yet its role in tumor growth and tumor sensitivity to DHA treatment remains unclear. We characterized the role of ACSL6 in regulating cell growth and DHA sensitivity in vitro cancer cells and in vivo xenograft tumors.
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PIVKA-II as a surrogate biomarker for therapeutic response in Non-AFP-secreting hepatocellular carcinoma - BMC Cancer

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By San-Chi Chen, Hsiang-Ling Ho, Chien-An Liu, Nai-Jung Chiang, Muh-Hwa Yang
| BMC Cancer Verified
San-Chi Chen participated in the study conception, study design, data collection, data analysis and interpretation, and drafting of the manuscript. Hsiang-Ling Ho and Yee Chao participated in the lab data collection and analysis. Chien-An Liu and Yee Chao were responsible for interpreting the imaging and evaluating the treatment efficacy. Yi-Ping Hung, Nai-Jung Chiang, Ming-Huang Chen participated in the study design and critical revision of the manuscript.
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Comparative impact of tertiary lymphoid structures and tumor-infiltrating lymphocytes in cholangiocarcinoma

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By Yi-Chen Yeh, Chien-Jung Huang, Nai-Jung Chiang, Shin-Yi Chung
| The BMJ Verified
Methods The present study included patients who had received a histologically confirmed diagnosis of locally advanced or metastatic biliary tract cancer at any of the participating hospitals (assessed on the basis of the Response Evaluation Criteria in Solid Tumors (V.1.1)). Other clinical data were obtained from a relevant study.7 The patients received fixed-dose therapy (nivolumab, 200 mg; gemcitabine, 800 mg/m2; and S-1, 80/100/120 mg) on day 1 of a 2-week cycle.
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