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Nakyung Koo on Muck Rack

Nakyung Koo

As seen in: Nature
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Articles

Antigen presentation by CD40 + MHC-II + astrocytes promotes CNS autoimmunity

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By Joon-Hyuk Lee, Zhaorong Li, Joselyn S. Soto, Ah-Ram Kim, Tomer Illouz, Carolina M. Polonio, Michael Kilian Verified, Jessica E. Kenison, Anton M. Schüle, Camilo Faust Akl, Hong-Gyun Lee, Brian Andersen, Jessica J. Ye, Joseph M Rone, Gavin Piester, Jazmín Belén Martínez, Jinsu Lee, Tae Hyun Heo, Elizabeth Chung, Landon K. Oetjen, Pere Duart-Abadia, Norbert Perrimon, Michael Wheeler, Baljit S. Khakh, Stéphanie Zandee, Alexandre Prat, Francisco J. Quintana, Lena Srun, Austin Danko, Nakyung Koo
| Nature Verified
Abstract Astrocytes contribute to the pathology of multiple neurological disorders, including the T cell-driven autoimmune disease of the central nervous system (CNS) multiple sclerosis and its mouse model, experimental autoimmune encephalomyelitis1. However, little is known about functional interactions between astrocytes and CD4+ T cells.
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