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Namdev S. Togre on Muck Rack

Namdev S. Togre

As seen in: Frontiers, MDPI, Preprints.org
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Articles

Alcohol and E-Cigarette Activate P2X7R in Lung Epithelial Cells, Stimulating Release of Plasminogen Activator in Extracellular Vesicles Injuring Blood-Brain Barrier

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By Naveen Mekala, Namdev S. Togre, Sunil M. Kurian
| Preprints.org
Submitted: 07 September 2026 Posted: 08 September 2026 You are already at the latest version Chronic exposure to ethanol (ETH) and e-cigarette vapor activates the P2X7 receptor (P2X7R) in human pulmonary alveolar epithelial cells (hPAEpiCs), promoting extracellular vesicle (EV) release. Proteomic analysis of this EVs identified enrichment of urokinase-type plasminogen activator (uPA), a key extracellular matrix remodeling enzyme.
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P2X7R Signaling and Differential Regulation of Neuroinflammatory and Behavior Responses In male and Female Mice During Chronic Ethanol Exposure

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By Namdev S. Togre, Priyanka S. Bhoj, Naveen Mekala, Jayshil Trivedi
| Preprints.org
Submitted: 27 January 2026 You are already at the latest version Chronic alcohol exposure disrupts blood-brain barrier (BBB) integrity and promotes neuroinflammation, with P2X7 receptor (P2X7R) signaling playing a critical role. Our prior work in male mice linked P2X7R inhibition to reduced extracellular ATP (eATP) release, modulated extracellular vesicle (EV) cargo, and attenuated neuroinflammation in chronic intermittent ethanol (CIE)-exposed mice.
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Tissue Kallikrein-1 Suppresses Type I Interferon Responses and Reduces Depressive-Like Behavior in the MRL/lpr Lupus-Prone Mouse Model

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By Priyanka S. Bhoj, Namdev S. Togre, Cassandra Nocito, Malika Winfield
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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