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Articles

Cisplatin binding to angiogenin protein: new molecular pathways and targets for the drug's anticancer activity

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By Giarita Ferraro, Vanessa Sanfilippo, NanoHybrid BioInterfaces Laboratory, Lorenzo Chiaverini
| Royal Society of Chemistry Verified
Cisplatin binding to angiogenin protein: new molecular pathways and targets for the drug's anticancer activity† Giarita Ferraro, a Vanessa Sanfilippo, b Lorenzo Chiaverini, c Cristina Satriano, *b Tiziano Marzo, *c Antonello Merlino *a and Diego La Mendola c Abstract Cisplatin (CisPt), a platinum-based chemotherapeutic widely used in the treatment of various cancers, has multiple mechanisms of action, including nuclear DNA (nDNA) and mitochondrial DNA (mDNA) damage and cytoskeletal...
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