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Articles by Nathan Perlis
The use of focal therapy for the treatment of prostate cancer in Canada
Abstract Introduction: Focal therapy is an emerging treatment for localized prostate cancer. The objectives of this review were to: 1) review how focal therapies are regulated and approved; 2) summarize the scope and quality of the literature regarding safety, efficacy, and side-effects; and 3) outline ongoing clinical trials of focal therapy in Canada.
Value of Dynamic Contrast-Enhanced MRI for Grade Group Prediction in Prostate Cancer: A Radiomics Pilot Study
To determine the role of dynamic contrast-enhanced (DCE) MRI-radiomics in predicting the International Society of Urological Pathology Grade Group (ISUP-GG) in therapy-naïve prostate cancer (PCa) patients. In this ethics review board-approved retrospective study on two prospective clinical trials between 2017 and 2020, 73 men with suspected/confirmed PCa were included. All participants underwent multiparametric MRI. On MRI, dominant lesions (per PI-RADS) were identified.
Development, multi-institutional external validation, and algorithmic audit of an artificial intelligence-based Side-specific Extra-Prostatic Extension Risk Assessment tool (SEPERA) for patients undergoing radical prostatectomy: a retrospective cohort stu
Summary Background Accurate prediction of side-specific extraprostatic extension (ssEPE) is essential for performing nerve-sparing surgery to mitigate treatment-related side-effects such as impotence and incontinence in patients with localised prostate cancer. Artificial intelligence (AI) might provide robust and personalised ssEPE predictions to better inform nerve-sparing strategy during radical prostatectomy.
Prostate cancer diagnosis: Pushing boundaries while understanding the limitations of current technologi
License You, the Author(s), assign your copyright in and to the Article to the Canadian Urological Association.
Target prostate biopsies: How best to report in synoptic format?
You, the Author(s), assign your copyright in and to the Article to the Canadian Urological Association.
Role of multiparametric MRI in long-term surveillance following focal laser ablation of prostate cancer | The British Journal of Radiology
1. Key Statistics for Prostate CancerAmerican Cancer Society, Atlanta.. Available from: https://www.cancer.org/cancer/prostate-cancer/about/key-statistics. 2. NICE Guidance - Prostate cancer: diagnosis and management: © NICE (2019) Prostate cancer: diagnosis and management. BJU Int 2019; 124: 9–26. doi: https://doi.org/10.1111/bju.14809 http://www.ncbi.nlm.nih.gov/pubmed/31206997 3. Klotz L, , Vesprini D, , Sethukavalan P, , Jethava V, , Zhang L, , Jain S, , et al..
Case - Reflex anuria: A rare complication of retrograde pyelography
You, the Author(s), assign your copyright in and to the Article to the Canadian Urological Association.
Creating patient-centered radiology reports to empower patients undergoing prostate magnetic resonance imaging
Perlis, N., Finelli, A., Lovas, M., Berlin, A., Papadakos, J., Ghai, S., Bakas, V., Alibhai, S., Lee, O., Badzynski, A., Wiljer, D., Lund, A., Di Meo, A., Cafazzo, J., & Haider, M. (2020). Creating patient-centered radiology reports to empower patients undergoing prostate magnetic resonance imaging. Canadian Urological Association Journal, 15(4), 108-13. https://doi.org/10.5489/cuaj.6585
Diagnostic utility of axial imaging in the evaluation of hematuria: A systematic review and critical appraisal of the literature
Christopher J.D. Wallis Rashid K. Sayyid Roni Manyevitch Nathan Perlis Vinata B. Lokeshwar Neil E. Fleshner Martha K. Terris Matthew E. Nielsen Zachary Klaassen Keywords: Hematuria; Urologic Neoplasms; Diagnostic Imaging Abstract Introduction: Increasing severity of hematuria is instinctively associated with higher likelihood of urological malignancy.
How small changes can propel more effective and safe healthcare delivery
Nathan Perlis Keywords: Antibiotic prophylaxis, commentary, fosfomycin, ciprofloxacin, transrectal ultrasound-guided prostate needle biopsy Published 2020-08-03 You, the Author(s), assign your copyright in and to the Article to the Canadian Urological Association.
Case ‒ Foamy high-grade prostatic intraepithelial neoplasia: A false positive for prostate cancer on multiparametric magnetic resonance imaging?
The introduction of multiparametric magnetic resonance imaging (mpMRI) of the prostate, and specifically the introduction of diffusion-weighted imaging (DWI), has significantly impacted the diagnosis of prostate cancer and the management of clinically localized prostate cancer. Indeed, its localizing ability has now opened up opportunities to target focal lesions in partial gland ablation therapy as a treatment option for localized prostate cancer.
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