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Professor and Chair Division of Urology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Canada
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CAIX carbonic anhydrase IX CCRCC clear cell renal cell carcinoma ChRCC chromophobe renal cell carcinoma EVT eosinophilic vacuolated tumour IHC immunohistochemistry LOT low-grade oncocytic tumour NOS not otherwise specified RCC renal cell carcinoma RMB renal mass biopsy SDHB succinate dehydrogenase subunit B Introduction Renal mass biopsy (RMB) is increasingly recognized as an important tool in the evaluation and management of renal masses.1 While 10%–30% of small renal masses (≤4 cm) are...
Discussion The classification of tumours with oncocytic/eosinophilic morphology has evolved significantly in recent years with the recognition of several new and emerging tumour entities. The recent WHO classification introduced a category of ‘other oncocytic tumours’ to describe a heterogeneous group of neoplasms that are not classifiable as oncocytoma or ChRCC.
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