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Nathaniel Barton

As seen in: MDPI, BioRxiv
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Articles

Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer’s Disease and Autoimmune Diseases

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By Jonathan Sundstrom, Emma Vanderleeden, Nathaniel Barton, Sambra D. Redick
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Transcripts Associated with Alzheimer’s Disease and Autoimmune Diseases

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By Jonathan Sundstrom, Nathaniel Barton, Sambra D. Redick, Emma Vanderleeden
| preprints.org
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 15 July 2024 / Approved: 16 July 2024 / Online: 16 July 2024 (08:27:19 CEST) Sundstrom, J.; Vanderleeden, E.; Barton, N. J.; Redick, S. D.; Dawes, P.; Murray, L. F.; Olson, M. N.; Tran, K.; Chigas, S. M.; Orszulak, A. R.; Church, G. M.; Readhead, B.; Oh, H.; Harlan, D. M.; Knipe, D. M.; Wang, J. P.; Chan, Y.; Lim, E. T.
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Unbiased multiplex antigen screening of Cerebrospinal Fluid detects microbial and autoantigenic epitopes associated with Multiple Sclerosis

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By Nathaniel Barton, Khanh Tran, Meagan N Olson, Mugdha Deshpande
| BioRxiv
Abstract To comprehensively investigate the intrathecal antibody profile of multiple sclerosis (MS), we examined the cerebrospinal fluid of 195 patients (92 MS and 103 non-MS) for antibodies using a multiplex unbiased bacteria peptide library. We first tested against Epstein-Barr nuclear antigen 1 (EBNA1) for epitope sites enriched in MS and found a significant enrichment at position 407-419.
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