Nathaniel Chin on Muck Rack

Nathaniel Chin

Madison
As seen in: Dementia Matters, Color Research & Application, Wiley Online Library, Alzheimer's Research and Therapy, JAMA Network, JAMA: Journal of the American Medical Association, Medscape, The New England Journal of Medicine, Newsday, Wisconsin State Journal, The Lancet
Memory clinic doc @UWHealth. #Alzheimers and #dementia investigator @WisconsinADRC. Host of #DementiaMatters podcast. Grad of @uwsmph. #medtwitter #somedocs
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Articles

Beyond Binary—The Case for Amyloid Centiloid Quantification

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By Nathaniel Chin, Claire M. Erickson, Joshua D. Grill, Gil D. Rabinovici
| JAMA: Journal of the American Medical Association Verified
In patients with mild cognitive impairment or dementia, amyloid positron emission tomography (PET) can estimate cerebral amyloid burden, inform etiologic diagnosis, and help determine eligibility for amyloid-targeting therapies.1 Despite recent US Food and Drug Administration (FDA) clearance of software that quantifies amyloid PET on the Centiloid scale, a numeric estimate of global cortical amyloid plaque burden, results are typically communicated as a binary positive or negative.
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Importance of Function for Alzheimer Diagnosis and Management

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By Nathaniel Chin
| JAMA Network Verified
The Food and Drug Administration approval of 2 blood tests to detect amyloid plaques marks a breakthrough moment for Alzheimer disease.1 Compared with diagnostics based on cerebrospinal fluid or positron emission tomography imaging, blood biomarkers are much more accessible and provide a more streamlined path to potential treatments and clinical trials. Yet, the growing enthusiasm for biomarkers risks obscuring a fundamental truth: biomarkers only reflect disease pathology.
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How to Treat Alcohol Use and Mental Health Together

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By Noelle K. LoConte, Kristine Torres-Lockhart, Nathaniel Chin
| Medscape Verified
Summary and Key Takeaways Dr Torres-Lockhart walks through the complex interplay between alcohol use and mental health conditions like anxiety, depression, and bipolar disorder. Sometimes alcohol use is primary; other times, it’s a coping mechanism for existing psychiatric conditions. Regardless of which came first, physicians must treat both simultaneously.
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