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PKA Regulates PINK1 Stability and Parkin Recruitment to Damaged Mitochondria through Phosphorylation of MIC60
Figure 6Phosphorylation of MIC19 by PKA Controls Parkin Recruitment(A) Cells transfected with siRNA for Luc, MIC60, MIC19, MIC25, MIC10, MIC27, or MIC26 were subjected to analysis by immunoblot using the indicated antibodies.(B) GFP-Parkin/HeLa cells transfected with siRNA as described for (A) were CCCP-treated, and the intracellular localization of GFP-Parkin was analyzed.(C) Cells transfected with siRNA targeting either 3′-UTR or open reading frame (ORF) of MIC19 were subjected to analysis...
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