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Nenad Bartonicek on Muck Rack

Nenad Bartonicek

As seen in: Genome Medicine, Cell Press
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Articles

A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation

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By Jennifer R. Devlin, Ben Martin Verified, Nenad Bartonicek, Keziah Ting, Zheng Fan, Izabela Todorovski, Filip Bjelosevic, Sandra Verschoor, Annette Ciccone, Joseph Trapani, Attila Horvath, Emily Tinsley, Peter Fraser, Andrea Newbold, Jarrod J. Sandow, Andrea M. Muscat, Kaylene J. Simpson, Matthias Geyer, Stephin J. Vervoort, Ricky W. Johnstone
| Cell Press Verified
Keywords gene-expression cyclin-dependent kinases RNA polymerase II transcription cycle cancer therapy Introduction RNA polymerase II (Pol II) transcription is tightly controlled at multiple levels with discrete molecular checkpoints engaged to precisely regulate gene expression.1,2 Pol II transcription dysregulation may be considered a universal feature of cancer cells, fueling accelerated proliferation, enhanced survival, aberrant metabolism, and increased invasion/migration.3,4,5...
Open in Who Shared Issue with article?

Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis

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By Sunny Wu, Daniel L Roden, Ghamdan Al-Eryani, Nenad Bartonicek
| Genome Medicine Verified
Sunny Z. Wu ORCID: orcid.org/0000-0002-6153-04491,2, Daniel L. Roden1,2, Ghamdan Al-Eryani1,2, Nenad Bartonicek1,2, Kate Harvey1, Aurélie S. Cazet1,2, Chia-Ling Chan1,3, Simon Junankar1,2, Mun N. Hui1,4, Ewan A. Millar5,6,7, Julia Beretov5,8, Lisa Horvath1,4,9, Anthony M. Joshua1,10, Phillip Stricker10, James S. Wilmott11,12, Camelia Quek11,12, Georgina V. Long11,12,13, Richard A. Scolyer ORCID: orcid.org/0000-0002-8991-001311,12,14, Bertrand Z.
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