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Neuroinfectious Disease

As seen in: Frontiers, Multiple Sclerosis and Related Disorders
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Articles

Optimizing animal models of autoimmune encephalitis using active immunization

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By Neuroinfectious Disease, Jalali Motlagh, A Arturo Leis, Chih-Chung Jerry
| Frontiers
Introduction Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis (NMDARE) (1), the most common form of autoimmune encephalitis (AE), is a devastating neuropsychiatric disorder characterized by antibodies (Abs) to NMDARs being present in the serum and/or cerebrospinal fluid (CSF) of patients.
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Treatment of IgG4-related disease-associated hypertrophic pachymeningitis with intrathecal rituximab: a case report

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By Neuroinfectious Disease, Yolanda Aladro, Robert Weissert MD
| Frontiers
1. Introduction IgG4-related disease-associated hypertrophic pachymeningitis (IgG4RD-HP) is a fibroinflammatory disorder in which a combination of peripheral and intrathecal inflammation may play a role (1). The first-line treatment for IgG4-RD is glucocorticoids. Intravenous rituximab is a second-line therapy but has limited ability to penetrate the blood-brain barrier. Intrathecal rituximab has been reported to lead to clinical improvement in IgG4-RD-HP (2, 3).
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Treatment of IgG4-Related Disease-Associated Hypertrophic Pachymeningitis with Intrathecal Rituximab: A Case Report

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By Neuroinfectious Disease, John Henry
| Frontiers
Denis T. Balaban1*, Spencer K. Hutto2, Bruno P. Panzarini3, Aileen O'Shea3, Aditi Varma1, Pamela S. Jones4, Bart K. Chwalisz1, 5, John H.
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