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Nicki F. Schindler on Muck Rack

Nicki F. Schindler

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Articles

NF1 mutation drives neuronal activity-dependent initiation of optic glioma

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By Jared D. Hysinger, Tara Barron, Nicki F. Schindler
| Nature Verified
Abstract Neurons have recently emerged as essential cellular constituents of the tumour microenvironment, and their activity has been shown to increase the growth of a diverse number of solid tumours1. Although the role of neurons in tumour progression has previously been demonstrated2, the importance of neuronal activity to tumour initiation is less clear—particularly in the setting of cancer predisposition syndromes.
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