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Tara Barron on Muck Rack

Tara Barron

As seen in: Nature
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Articles

Levetiracetam therapeutically targets GABAergic synapses in diffuse midline glioma

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By Tara Barron, Richard Drexler, Aaron Y. Mochizuki, Evan Cantor, Kiarash Shamardani, Pamelyn J. Woo, Neeraj Soni, Dana Tlais, Andrea T. Franson, Samantha Lyons, Truman Knowles, Vilina Mehta, Michael A. Quezada, Michael B. Keough, Samin Jahan, Linh Vo, linh võ, Enrique Castañeda, Kathryn Taylor, Lijun Ni, Samuel Wu, Franz Ricklefs, Ulrich Schüller, Sabine Mueller, Paul Fisher, Cynthia J. Campen, Hannes Vogel, Sonia Partap, Kai Kaila, Carl Koschmann, Michelle Monje, Shannon Raber, Kim Kilian
| Nature Verified
Abstract Antiseizure medications, such as levetiracetam, are commonly used in glioma patients. Retrospective analyses evaluating effects of antiseizure medications on glioma patient survival have yielded inconsistent results, probably due to confounding factors of glioma subtype and drug class.
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NF1 mutation drives neuronal activity-dependent initiation of optic glioma

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By Jared D. Hysinger, Tara Barron, Nicki F. Schindler
| Nature Verified
Abstract Neurons have recently emerged as essential cellular constituents of the tumour microenvironment, and their activity has been shown to increase the growth of a diverse number of solid tumours1. Although the role of neurons in tumour progression has previously been demonstrated2, the importance of neuronal activity to tumour initiation is less clear—particularly in the setting of cancer predisposition syndromes.
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