Niclas Thomas

Fine needle aspirates comprehensively sample intrahepatic immunity Upkar S Gill1, Laura J Pallett2, Niclas Thomas2, Alice R Burton2, Amit A Patel3, Simon Yona3, Patrick T F Kennedy1, Mala K Maini2 1 Barts Liver Centre, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK 2 Division of Infection and Immunity, Institute of Immunity and Transplantation, University College London, London, UK 3 Division of Medicine, University...

Fine needle aspirates comprehensively sample intrahepatic immunity Upkar S Gill1, Laura J Pallett2, Niclas Thomas2, Alice R Burton2, Amit A Patel3, Simon Yona3, Patrick T F Kennedy1, Mala K Maini2 1 Barts Liver Centre, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK 2 Division of Infection and Immunity, Institute of Immunity and Transplantation, University College London, London, UK 3 Division of Medicine, University...

Significance of this study What is already known on this subject? Many important immune cell types accumulate preferentially within the intrahepatic compartment. There are also liver-resident populations of NK cells and memory T cells, including HBV-specific CD8 providing sentinel front-line immunosurveillance, that cannot be sampled in the blood.