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Niklas Rye Jørgensen on Muck Rack

Niklas Rye Jørgensen

As seen in: BMJ Open, MDPI, Cell Reports Medicine, Politiken, Seizure - European Journal of Epilepsy
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Articles

Glucocorticoid-induced changes of the gut microbiota and metabolic markers in healthy young men: Outcome of a randomized controlled trial

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By Liwei Lyu, Yong Fan, Thomas Bryrup, Marc Clos-Garcia, Susanne Brix, Evelina Stankevic, Asger Lund, Filip Krag Knop, Niklas Rye Jørgensen, Henrik Vestergaard, Torben Bo Hansen, Tue H. Hansen, Trine Nielsen, Oluf Borbye Pedersen, Markus Eiken
| Cell Reports Medicine Verified
ArticleOnline now102426Open access 1Center for Clinical Metabolic Research, Herlev-Gentofte University Hospital, Hellerup, Denmark 2Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark 3Department of Biotechnology and Biomedicine, Technical University of Denmark, Kgs.
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Expression of the Purinergic Receptor P2X7 Receptor in Murine MOPC315.BM Myeloma Cells

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By Melisa Demir, Niklas Rye Jørgensen, Eva Risborg Høyer, Lasse Kristoffer Bak
| MDPI
1. Introduction Adenosine-5′ triphosphate (ATP) and its derivatives support, as chemical messengers, purinergic transmission throughout tissues and species. As an extracellular messenger, eATP activates P2X receptors (P2XR), a family of trimeric non-selective cation channels. The P2X7 receptor subtype has attracted the interest of major drug discovery projects since being cloned from a rat brain cDNA library [1].
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Automated Interlaboratory Comparison of Therapeutic Drug Monitoring Data and Its Use for Evaluation of Published Therapeutic Reference Ranges

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By Niklas Rye Jørgensen, Jens Borggaard Larsen, Elke Hoffmann-Lücke, Per Hersom Aaslo
| MDPI
Abstract : Therapeutic drug monitoring is a tool for optimising the pharmacological treatment of diseases where the therapeutic effect is difficult to measure or monitor. Therapeutic reference ranges and dose-effect relation are the main requirements for this drug titration tool. Defining and updating therapeutic reference ranges are difficult, and there is no standardised method for the calculation and clinical qualification of these.
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