Nimalan Arinaminpathy

Commission recommendations In a restatement of recommendations made in the original Commission report, we call for all countries to invest in tuberculosis not only as a moral imperative, but as an effective fortification against other pandemics and a central component of universal health coverage.

1. Introduction Decades of effort and resources have seen the burden of tuberculosis (TB) fall steadily across low- and lower–middle-income countries (LLMCs).Footnote 1 From 1990 to 2019, the incidence of TB in these countries fell from 285 cases per 100,000 to 176 cases per 100,000, while deaths fell from 63 per 100,000 to 46 per 100,000 (IHME, 2021). Despite these steady improvements, TB remained the world’s most deadly infectious disease before the COVID-19 pandemic.

Information Published In Science Volume 376 | Issue 6592 29 April 2022 Copyright Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. This is an article distributed under the terms of the Science Journals Default License. Submission history Received: 3 February 2022 Accepted: 25 March 2022 Published in print: 29 April 2022 Permissions Request permissions for this article.