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Nina Lin

  • Executive Producer, Redacted
As seen in: Nature, NBC News, New York Daily News, Journal of Women & Aging, ACS Publications, Yahoo Sports, WNBC-TV (New York, NY), WCAU-TV (Philadelphia, PA), KNBC-TV (Los Angeles, CA), KXAS-TV (Fort Worth, TX) and
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Articles

mRNA-based influenza vaccine expands the B cell response breadth in humans

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By Hanover C. Matz, Tae-Geun Yu, Kritika Dixit, Caroline Kikawa, Julian Q. Zhou, Garazi Pena Alzua, Lowrey Peyton, Anders K. Madsen, Fangjie Han, Ariana Ghez Farrell, Robert Hoelzl, Aaron J. Schmitz, Stephen Horvath, Hunter K Keplinger, Benjamin S. Strnad, Mark J. Hoegger, William Middleton, Michael K. Klebert, Nina Lin, Raffael Nachbagauer, Florian Krammer, Robert M. Paris, Jesse Bloom, Jackson Turner, Rachel M. Presti, Jiwon Lee, Ali H Ellebedy
| Nature Verified
Abstract Conventional influenza virus vaccines induce antibody responses of limited breadth. Whether mRNA-based influenza virus vaccines can induce a superior germinal center (GC) response in humans remains unclear. Here we assessed B cell responses in an observational study of cohorts of healthy young adults receiving a licensed, split-virion or investigative mRNA-based quadrivalent seasonal influenza virus vaccine over two consecutive seasons.
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Cell-Membrane-Anchored Synthetic Dynamic DNA Circuits for Signaling Transient Cell Migration

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By Nina Lin, Yu Ouyang, Yunlong Qin, Songqin Liu
| ACS Publications
Introduction Click to copy section linkSection link copied! Communication between cells and their exterior environment is a key feature regulating physiological processes, such as differentiation, (1) migration, (2) apoptosis, (3) cell intercommunication, (4−6) and cellular metabolism.
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Microbiota-driven antitumour immunity mediated by dendritic cell migration

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By Nina Lin, Shota Fukuoka, Shohei Koyama, Daisuke Motooka, Dieter M. Tourlousse, Yuko Shigeno, Yuki Matsumoto, Kazutoshi Murotomi, Hideyuki Tamaki, Takuma Irie, Eri Sugiyama, Shogo Kumagai, Kota Itahashi, Tokiyoshi Tanegashima, Sachiko Ito, Takahiro Tsuji, Hiroaki Wake, Keisuke Watanabe, Yuka Maeda, Tomohiro Enokida, Makoto Tahara, Riu Yamashita, Takao Fujisawa, Motoo Nomura, Akihito Kawazoe, Koichi Goto, Toshihiko Doi, Kohei Shitara, Hiroyuki Mano, Yuji Sekiguchi, Shota Nakamura, Hiroyoshi Nishikawa, Hiroyuki Yamano, Kaori Fujimaki, Mariko Shindo, Yoshimi Benno
| Nature Verified
Abstract Gut microbiota influence the antitumour efficacy of immune checkpoint blockade1,2,3,4,5,6, but the mechanisms of action have not been fully elucidated. Here, we show that a new strain of the bacterial genus Hominenteromicrobium (designated YB328) isolated from the faeces of patients who responded to programmed cell death 1 (PD-1) blockade augmented antitumour responses in mice.
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