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Articles by Ning Han
Patient-reported treatment burden, communication, and persistence intention during add-on peginterferon alfa-2b therapy for chronic hepatitis B: a cross-sectional study
Abstract Background: Add-on peginterferon alfa-2b (Peg-IFN) may help reduce hepatitis B surface antigen levels and achieve a functional cure in selected patients with chronic hepatitis B (CHB), but the treatment burden can make a finite course difficult to complete. We examined the patient-reported factors associated with thoughts of discontinuation and intentions to persist with treatment during add-on Peg-IFN therapy.
Orbital Coupling-Induced Quasi-Covalent Interaction in Nd-Doped L1 2 -Pt 3 Co Intermetallic Catalysts for Durable Fuel Cells
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm78832-sup-0001-SuppMat.docx37.6 MB Supporting File: adfm78832-sup-0001-SuppMat.docx.
Boundary-induced three-dimensional one-way bulk transport in gyromagnetic systems
Abstract In three-dimensional (3D) topological physics, the bulk properties of a material fundamentally determine the existence and characteristics of its boundary states. However, these boundary-state fields are usually localized near the interface of the bulk, thereby losing their high-throughput information processing capabilities and the controllability of their mode width.
Season-adjusted longitudinal changes in serum 25-hydroxyvitamin D during pegylated interferon add-on to ongoing tenofovir alafenamide therapy in chronic hepatitis B: a real-world cohort study
Abstract Objectives: To characterize serum 25-hydroxyvitamin D [25(OH)D] trajectories during peginterferon alfa-2b (Peg-IFN) add-on to ongoing tenofovir alafenamide (TAF) therapy in chronic hepatitis B and explore associations with hepatitis B surface antigen (HBsAg). Methods: This retrospective cohort identified 203 consecutive patients, of whom 190 contributed longitudinal data through week 48.
ZIF-Derived FeCo Nanoparticles and FeN 4 Single-Atom Sites for High-Performance Oxygen Evolution and Oxygen Reduction Bifunctional Electrocatalysis
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Data will be made available on request. Supporting Information Filename Description cssc70886-sup-0001-SuppData-S1.pdf2 MB Supplementary Material References 1, , , et al., “De Novo Generation of Hit-Like Molecules from Gene Expression Signatures Using Artificial Intelligence,” Nature Communications 11 (2020): 10.
Paper-based lead-free thin film X-ray detectors with high sensitivity and superior environmental stability
Abstract Low-dimensional, lead-free halide perovskites are promising candidates for next-generation radiation detectors due to their favorable optoelectronic properties and environmental safety. Among them, Cs3Bi2Br9 has thus attracted significant attention for its layered structure and intrinsic stability. Although Cs3Bi2Br9 has already been explored for X-ray detection, simple and scalable fabrication routes for its thin films on flexible low-cost substrates remain underdeveloped.
Combined Use of Tryptophan and Fu Brick Tea in Low Doses Promotes Weight Loss in Mice by Modulating AhR-Mediated Tryptophan Metabolism and Reshaping the Gut Microbiota Click to copy article link Article link copied!
Cite Jump to ExpandCollapse Bioactive Constituents, Metabolites, and FunctionsApril 7, 2026 Combined Use of Tryptophan and Fu Brick Tea in Low Doses Promotes Weight Loss in Mice by Modulating AhR-Mediated Tryptophan Metabolism and Reshaping the Gut Microbiota Click to copy article linkArticle link copied! Ning Han Ning Han Shaanxi Engineering Laboratory for Food Green Processing and Safety Control, and Shaanxi Key Laboratory for Hazard Factors Assessment in Processing and Storage of...
Artificial intelligence as a driver of sustainable materials and circularity
Artificial intelligence is transforming materials research, yet its potential for sustainability remains underexploited. Artificial intelligence can enable circular materials systems by integrating materials performance, life-cycle assessment and sustainability metrics across design, use and recycling, accelerating the transition from linear innovation to closed-loop materials economies.
Computer Science > Computer Vision and Pattern Recognition
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Stroke progression index as a dynamic metric is associated with functional outcome in progressive ischemic stroke with large vessel occlusion
Abstract Objective: Current evaluation of progressive ischemic stroke (PIS) with large vessel occlusion (LVO) relies on static clinical or imaging measures and lacks quantitative assessment of dynamic neurological deterioration. We proposed a novel metric, stroke progression index (SPI), to assess its association with clinical outcomes and benefit from endovascular treatment (EVT), and to explore its potential clinical relevance.
Hysteretic self-oscillatory acoustic radiation with tunable orbital angular momentum
Abstract Vortex beams carrying orbital angular momentum (OAM) have attracted growing attention across fields, including optics and acoustics, for potential applications in particle manipulation and high-speed communication. Intracavity generation of OAM beams, such as OAM lasers, efficiently produces high-power, high–beam-quality vortices. This scheme, however, remains rarely explored in acoustics.
📚 My 2025 Learning Plan & Hands-On Projects in Data, AI, and Engineering
As I transition into a more team-focused role at work, I want to stay close to what I love: building, learning, and experimenting with cutting-edge technologies. This year, I’m committing to deepening my knowledge across systems design, machine learning, distributed computing, and scalable software development. Here’s my roadmap for 2025 — both what I plan to learn and what I aim to build.
Staying Current: My 2025 Learning Journey in Data & AI
I recently wrapped up an exciting chapter as a tech consultant and just kicked off a brand-new role at one of the largest credit card companies in the U.S. After years in consulting, I’m used to living in the fast lane — juggling clients, shipping solutions, and constantly adapting to new tools and tech. But now, I’m stepping into something different… I spent the last few years working with major healthcare clients — where stakes are high, and timelines are tight.
Polyelectrolyte matrix-enabled multi-step energy transfer light-harvesting system for enhanced photocatalytic benzimidazole synthesis
Polyelectrolyte matrix-enabled multi-step energy transfer light-harvesting system for enhanced photocatalytic benzimidazole synthesis The natural photosynthesis system is characterized by multi-step sequential energy transfer process, and the construction of efficient and sequential artificial light-harvesting system (ALHS) to simulate the natural photosynthesis has become a research hotspot.
Characteristics and risk factors of drug‐resistant tuberculosis in Sichuan, China: An observational study
Corresponding Author Hong Tang Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu, Sichuan, China Laboratory of Infectious and Liver Diseases, Institution of Infectious Diseases, West China Hospital of Sichuan University, Chengdu, Sichuan, China Division of Infectious Diseases, State Key Laboratory of Biotherapy, Sichuan University, Chengdu, Sichuan, China Correspondence Yilan Zeng, Department of Hepatology, Public Health Clinical Center of Chengdu, Chengdu,...
Rodent Seed Dispersal Syndromes Follow a Downslope Trajectory, Counteracting the Climate Change‐Mediated Tree Line Elevational Shift Upwards
1 Introduction Rodent-mediated seed dispersal plays a vital role in ecosystem functionality and the persistence of biodiversity (Vander Wall 1990). Seeds transported to favorable new sites, and thus avoiding proximity- and density-dependent mortality, result in plant recruitment success and the colonization of new areas (Vander Wall 1990).
Boosting Electrocatalytic Nitrogen Reduction on Cobalt‐Based Perovskite via Regulating Reaction Pathway Through Donation‐Back‐Donation Modulation
Conflict of Interests The authors declare no conflict of interest. Supporting Information Filename Description anie202504601-sup-0001-SuppMat.docx15.6 MB Supporting Information References 1, , , , , , , , , , , , , , , Nat. Food 2020, 1, 648–658. 2, , , , , , , , , , , , , , , , Science 2021, 374, 758–762. 3, , , , Adv. Mater. 2021, 33, 2005721. 4, , , , , , , , , , Angew. Chem. Int. Ed. 2023, 62, e202213711. 5, , , Nat. Catal. 2023, 6, 415–424. 6, , , Adv. Energy Sustainability Res. 2021, 2, 2000043. 7, , Chem.
Boosting Electrocatalytic Nitrogen Reduction on Cobalt‐Based Perovskite via Regulating Reaction Pathway through Donation‐Back‐Donation Modulation
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Precisely Modulating Oxygen Vacancies Via Heterovalent Ions Substitution in Spinel‐Structured Phosphor for Versatile Applications
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202502793-sup-0001-SuppMat.docx1.1 MB Supporting Information References 1, , , , , , Nat. Mater. 2023, 22, 289. 2, , , , , , , Adv. Mater. 2022, 34, 2107962. 3, , , , , , , , , , , Angew. Chem., Int. Ed. 2023, 135, 202218670. 4, , , , , , , , , , , Adv. Mater. 2023, 35, 2307198. 5, , , , , , , , Small 2025, 21, 2404442. 6, , , , , , , Adv. Mater. 2023, 35, 2306501. 7, , , Angew. Chem., Int.
Supramolecular organic framework nanosheets for efficient singlet oxygen generation: A multilevel energy transfer approach for photocatalytic Minisci reactions
Supramolecular organic framework nanosheets for efficient singlet oxygen generation: A multilevel energy transfer approach for photocatalytic Minisci reactions Replicating the multistep and sequential energy transfer observed in natural photosynthesis, the development of artificial light-harvesting systems (LHSs) capable of sequential multistep energy transfer remains a challenging and active area of research.
Photo-assisted technologies for environmental remediation - Nature Reviews Clean Technology
Abstract Industrial processes can lead to air and water pollution, particularly from organic contaminants such as toluene and antibiotics, posing threats to human health. Photo-assisted chemical oxidation technologies leverage light energy to mineralize these contaminants. In this Review, we discuss the mechanisms and efficiencies of photo-assisted advanced oxidation processes for wastewater treatment and photothermal technologies for air purification.
Application of Interpretable Artificial Intelligence for Sustainable Tax Management in the Manufacturing Industry
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Tailoring functionalities: pore engineering strategies in porous organic cages for diverse applications
Tailoring functionalities: pore engineering strategies in porous organic cages for diverse applications Porous materials feature high specific surface areas, enhanced mass transfer efficiency, and altered material–guest interactions, significantly impacting their functionality. Pore engineering is a key strategy for developing materials with tailored pore structures and environments.
Combination Nanodrug Delivery Systems Facilitate the Syncretism of Chemotherapy with Immunotherapy to Promote Cancer Treatment
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202405752-sup-0001-SuppMat.docx4.8 MB Supporting Information References 1, , , , , MedComm – Oncology 2022, 1, 8. 2, , , et al., Coord. Chem. Rev. 2023, 484. 3, , , , , , , , , Cell Mol. Immunol. 2022, 19, 192. 4, , , Advanced NanoBiomed Research 2022, 3, 2200080. 5, , , , , , , , , J Control Release 2021, 336, 410. 6, , , Nat Rev Drug Discov 2022, 21, 509. 7, , , , , , , , , , Adv. Mater.
Combination Nanodrug Delivery Systems Facilitate the Syncretism of Chemotherapy with Immunotherapy to Promote Cancer Treatment
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202405752-sup-0001-SuppMat.docx4.8 MB Supporting Information References 1, , , , , MedComm – Oncology 2022, 1, 8. 2, , , et al., Coord. Chem. Rev. 2023, 484. 3, , , , , , , , , Cell Mol. Immunol. 2022, 19, 192. 4, , , Advanced NanoBiomed Research 2022, 3, 2200080. 5, , , , , , , , , J Control Release 2021, 336, 410. 6, , , Nat Rev Drug Discov 2022, 21, 509. 7, , , , , , , , , , Adv. Mater.
Nickel‐Nitrogen Doped MnO2 as Oxygen Reduction Reaction Catalyst for Aluminum Air Batteries
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Invasive Pulmonary Aspergillosis in Patients with HBV-Related Acute on Chronic Liver Failure
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
ECWS: Soil Salinity Measurement Method Based on Electrical Conductivity and Moisture Content
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
The Controlled Preparation of a Carrier-Free Nanoparticulate Formulation Composed of Curcumin and Piperine Using High-Gravity Technology
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Supplementation of Methionine Dipeptide Enhances the Milking Performance of Lactating Dairy Cows
Font Type: Arial Georgia Verdana Line Spacing: Column Width: This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Spatial Interaction of Local Government Debt: Evidence from China
1. Introduction The massive and rapid expansion of local government debt in China has attracted attention worldwide in recent years. Alshaib et al. (2023) [] point out that governments’ external debt obligation is an indicator of fiscal sustainability, which is essential for developing countries to achieve sustainable development. Having an appropriate amount of local government debt can provide funds to promote the sustainable development of the economy and society.
Non-Hermitian topological excitation transmission in the dimerized lattice with imaginary potential and nonreciprocal hopping
We investigate the topological edge transmission of excitation based on the one-dimensional Su-Schrieffer-Heeger lattice with purely imaginary on-site potential and nonreciprocal nearest-neighbor hopping. We find that, when the system has only the nonreciprocal intracell hopping, the topological excitation transmission can be implemented only when the localization direction of the non-Hermitian skin effect matches the localization direction of edge state.
Crop Leaf Phenotypic Parameter Measurement Based on the RKM-D Point Cloud Method
1. Introduction Phenotypic parameters such as leaf length, perimeter, and area are crucial indicators of crop growth dynamics [1]. The leaf length reflects the crop growth status and guides irrigation strategies, while the leaf perimeter and area correlate with photosynthetic efficiency and yield [2,3,4,5]. Across growth stages, leaf phenotypic parameters exhibit distinct trends.
Bavachin Rejuvenates Sensitivity of Colistin against Colistin-Resistant Gram-Negative Bacteria
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Study of a Novel Fluidized Bed Flotation Column with Enhanced Bubble Dispersion
1. Introduction A gas-liquid-solid three-phase fluidized bed flotation column defined in this study is a solid particle bed fluidized by compressed air flowing in parallel upward as the dispersed gas phase and water as the continuous liquid phase. Reese et al. [1] discussed the industrial applications of three-phase fluidized bed systems. The advantages of a three-phase fluidized bed system have been widely used in research involving chemistry, physics, and biochemistry [2,3].
Switchover from singlet oxygen to superoxide radical through a photoinduced two-step sequential energy transfer process
Switchover from singlet oxygen to superoxide radical through a photoinduced two-step sequential energy transfer process† The competitive nature of type II photosensitizers in the transfer of excitation energy for the generation of singlet oxygen (1O2) presents significant challenges in the design of type I photosensitizers to produce the superoxide anion radical (O2˙−).
Effects of long‐term different‐scale rice-duck farming on the growth and yield of paddy rice
• , , and , Modeling of duck density and complex stocking time in Rice-duck agroecosystems in terms of economic and ecological benefits . Math Probl Eng : – ( ). • , , , , , et al., Effects of the integration of mixed-cropping and rice-duck co-culture on rice yield and soil nutrients in southern China . J Sci Food Agric : – ( ). • , , , , , et al., A comparison of nitrogen transfer and transformation in traditional farming and the rice-duck farming system by 15N tracer method . Agronomy : ( ).
Effects of Fu Brick Tea Polysaccharides on Gut Microbiota and Fecal Metabolites of HFD/STZ-Induced Type 2 Diabetes Rats
Effects of Fu Brick Tea Polysaccharides on Gut Microbiota and Fecal Metabolites of HFD/STZ-Induced Type 2 Diabetes Rats The prevalence of type 2 diabetes mellitus (T2DM) has dramatically increased globally, and the antidiabetic effects and underlying mechanisms of the polysaccharides extracted from Fu brick tea (FBTP) were investigated in high-fat diet (HFD)/streptozotocin (STZ)-induced T2DM rats.
Evaluating the Antibacterial and Antivirulence Activities of Floxuridine against Streptococcus suis
4. Materials and Methods 4.1. Bacterial Strains and Drug All bacteria strains used in this study are listed in Table 1. Nine clinical isolates of S. suis were obtained from pig lungs and were isolated and preserved by our laboratory. S. suis was cultured using tryptic soya broth (TSB) or plated on tryptic soya agar (TSA). Floxuridine (CAS: 50-91-9) was purchased form Yuanye Biotechnology (Shanghai, China).
Engineering the unidirectional topological excitation transmission and topological diode in the Rice-Mele model
We show how to implement the unidirectional topological excitation transmission in the Rice-Mele model. We find that the unidirectional excitation transmissions can be implemented via the asymmetric gap states. We reveal that the asymmetric gap states are essentially induced by the breaking of generalized chiral symmetry and the gap state without band crossing determines the transmission direction.
Host-Guest Photosensitizer of a Cationic BODIPY Derivative and Cucurbit[7]uril for High-Efficiency Visible Light-Induced Photooxidation Reactions
RETURN TO ARTICLES ASAPPREVEnergy, Environmenta...Energy, Environmental, and Catalysis ApplicationsNEXT Xin-Long Li School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, P. R. China , * , Rong-Zhen Zhang School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, P. R. China , * Kai-Kai Niu School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, P. R.
Perspectives on achievements and challenges of oxygen transport dual‐functional membrane reactors
The integration of membrane separation processes with chemical reactions through oxygen transport dual-functional membrane reactors has attracted significant attention due to the potential for process intensification, which also can create a synergy between the two units. This approach holds promise for promoting green chemistry principles by reducing energy consumption and environmental pollution.
Tumor Angiogenesis in HBV-related Hepatocellular Carcinoma
Back to Journals » Journal of Hepatocellular Carcinoma » Volume 10 Authors Chen H, Cao D , Han N, Zhang M, Jiang W, Wang X, Zeng Q, Tang H Received 24 August 2023 Accepted for publication 8 December 2023 Published 27 December 2023 Volume 2023:10 Pages 2337—2353 DOI https://doi.org/10.2147/JHC.S436926 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr David Gerber Han Chen,1,2 Dan Cao,1,2 Ning Han,1,2 Mingming...
Electrosynthesis of Metal-Organic Framework Films with Well‐Defined Facets
Conflict of interest The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Comparison of immune responses in children with infectious mononucleosis caused by Epstein-Barr virus at different infection stages
ORIGINAL ARTICLE Bing Chena and Ning Han contributed equally to this article. Abstract Introduction Infectious mononucleosis (IM) is a common infectious disease in children mainly caused by Epstein–Barr virus (EBV) infection, followed by abnormal immune response, and resulting in serious complications. However, there are few clinical analyses of immune responses in children with IM at different stages.
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