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Articles by Ning Tan
Disconnection of the late Pliocene Agulhas Leakage from Atlantic Meridional Overturning Circulation
Abstract The strength of the Atlantic Meridional Overturning Circulation (AMOC), in terms of streamfunction, is considered to depend partly on salt supply from the Indian Ocean through Agulhas Leakage (AL). In turn, AL is regulated by the position of the Southern Ocean subtropical front, which creates the pathway of the leaking around the African continent.
Spatially resolved single-cell atlas reveals the macroevolutionary trajectory of animal hearts
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Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Abstract Animal hearts display diverse anatomical structures during adaptive evolution. Here, we present a multi-omics atlas of adult hearts from 27 species across chordates, arthropods, and mollusks. Joint analysis indicates that Bilateria hearts share a core gene repertoire, taking a stepwise “add-on” approach as a universal evolutionary strategy.
By Qing Ji, Eric Merrill, J. Elliott Campbell, Shanshan Lian, Wei Wang, Yaoxin Liu, Meina Lu, Wentao Han, Jiaxin Luo, Xuejiao Zhang, Yue Pang, Yuru Li, Yufeng Li, Xin Dang, Peiyan Wang, Yating Qin, Ning Tan, Fang Zhang, Jin Zhang, Shuai Gao, Runyi Zhang, Lidong Guo, Lei Jiang, Pengchong Zhang, Yuehuan Zhang
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CCR1-mediated monocyte chemotaxis in the immunopathology of primary Sjögren’s syndrome: multi-omics integration analysis and computational target prioritization implicating Polygonatum odoratum
Abstract Objective: Primary Sjögren’s syndrome (pSS) is a chronic systemic autoimmune disease with no specific etiological treatment. Polygonatum odoratum, a traditional yin-nourishing herb, is used in treating pSS, but its molecular mechanism remains unclear. This study aimed to explore the potential association of CCR1 with pSS immunopathology and to computationally assess its candidacy as a predicted target of P. odoratum.
A critical role of ocean–sea ice interactions in the pronounced warmth during the Miocene Climatic Optimum - Communications Earth & Environment
Abstract The Miocene Climatic Optimum was characterized by global mean temperatures 8-10 °C above the preindustrial level, yet such extreme warmth remains difficult to reproduce in climate models. Using two climate models (IPSL-CM5A2 and NorESM1-F) with updated boundary conditions, we show that the simulated climate of this interval strongly depends on ocean-ice dynamics.
Effect of Different Superplasticizers on Carbonation Behavior of C2S and C4A3S¯ in Calcium Sulfoaluminate Cement
Get full access to this article View all available purchase options and get full access to this article. Data Availability Statement All data, models, and code generated or used during the study appear in the published article. Acknowledgments This work was financially sponsored by the National Key R&D Program of China (2020YFC1910000) and the Natural Science Foundation of China (Grant No. 51978153). Author contributions: Zengmei Wang conceived and planned the experiments.
Temperature Effects on GaN/AlN Heterojunction in a Piezomagnetic and Piezoelectric Semiconductor Composite Fiber
Conflict of Interest The authors declare no conflict of interest. References 1 , , , , , Adv. Mater. 2015, 27, 4488. 2 , , , , , CrystEngComm 2019, 21, 6545. 3 , , , , Acta Mech. Solida Sin. 2020, 33, 663. 4 , , , , Phys. Status Solidi A 2020, 217, 1900621. 5 , , , , J. Appl. Phys. 2020, 128, 064503. 6 , , , , Int. J. Appl. Mech. 2020, 12, 2050085. 7 , , , , Phys. Status Solidi A 2023, 220, 2300578. 8 , , , , , , , Nano Lett. 2012, 12, 3701. 9 , , , , , , Adv. Mater. 2014, 26, 6767. 10 , , , , , , , , , , Adv. Mater.
The mutation of Japanese encephalitis virus envelope protein residue 389 attenuates viral neuroinvasiveness - Virology Journal
BHK-21 (baby hamster kidney), Vero (African green monkey kidney), and U87 (human glioma) cells were cultivated in Dulbecco’s modified Eagle’s medium(DMEM)supplemented with 10% fetal bovine serum in a humidified 5% CO2 atmosphere at 37 °C. The JEV SA14 strain (GenBank accession No. U14163) was created and kept in our lab before being passed into BHK-21 cells. All full-length cDNA clones of JEV mutants were constructed using a two-plasmid system, as described previously [13].
Methotrexate injection: An old drug with a newly developing landscape
1 INTRODUCTION Since the approval of methotrexate (MTX) for the treatment of rheumatoid arthritis (RA) by the United States Food and Drug Administration in 1988,1 the drug has been widely used in rheumatology for more than 35 years. In the history of RA treatment, MTX has been first positioned as a second-line drug and, subsequently, as a first-line drug and an anchor drug. It has, therefore, become an extensively recognized drug among rheumatologists worldwide.
Construction of A sqc6 Topology Ni‐Gd Framework Employing 2,2’‐Phosphinico‐dibenzoate and Oxalate: Structure and Magnetic Properties
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Filename Description zaac202300214-s1-SI_ZAAC.docx4.7 MB Supplementary
Study on Nonlinear Dynamic Responses of the p-n GaN/AlN Heterojunction in Piezoelectric Semiconductor Composite Fibers
Conflict of Interest The authors declare no conflict of interest. References 1 , , Mech. Adv. Mater. Struct. 2020, 28, 2131. 2 , , , , , IEEE Sens. J. 2015, 15, 5839. 3 , , , , , , , , , , , , , , , Energy Environ. Sci. 2015, 8, 2402. 4 , Adv. Mater. 2012, 24, 4632. 5 , , , , , , , , ACS Nano 2012, 6, 3760. 6 , Mater. Today 2007, 10, 20. 7 , , , Sci. China Technol. Sci. 2013, 56, 2615. 8 , Nano Res. 2008, 1, 1. 9 , , , , Mech. Adv. Mater. Struct. 2020, 29, 1449. 10 , , , , J. Appl. Phys. 2017, 122, 204502.
Simplified Rapid Hydration Prevents Contrast-Associated Acute Kidney Injury Among CKD Patients Undergoing Coronary Angiography:
JACC Journals › JACC: Interventions › Archives › Vol. 16 No. 12 Abstract Background Patients with chronic kidney disease (CKD) undergoing coronary angiography (CAG) are at high risk of contrast-associated acute kidney injury (CA-AKI) and mortality. Therefore, there is a clinical need to explore safe, convenient, and effective strategies for preventing CA-AKI.
Noninvasive Methods for Detecting Advanced Liver Fibrosis
Back to Journals » Infection and Drug Resistance » Volume 16 Authors Cheng R, Tan N, Luo H, Kang Q, Xu X Received 17 June 2023 Accepted for publication 14 September 2023 Published 25 September 2023 Volume 2023:16 Pages 6323—6331 DOI https://doi.org/10.2147/IDR.S426374 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Suresh Antony Ran Cheng,1 Ning Tan,2 Hao Luo,2 Qian Kang,2 Xiaoyuan Xu3 1Department of...
Mesenchymal Stem Cells Pretreated with Collagen Promote Skin Wound-Healing
Open AccessArticle by †, †, , , , , , , , , and * College of Veterinary Medicine, Shaanxi Centre of Stem Cells Engineering & Technology, Northwest A & F University, Yangling, Xianyang 712100, China * Author to whom correspondence should be addressed. † These authors contributed equally to the paper. Int. J. Mol. Sci.
Hydration for prevention of kidney injury after primary coronary intervention for acute myocardial infarction: a randomised clinical trial
Hydration for prevention of kidney injury after primary coronary intervention for acute myocardial infarction: a randomised clinical trial http://orcid.org/0000-0003-2224-4885Yong Liu1,2, Ning Tan1,2, Yong Huo3, Shiqun Chen1,2, Jin Liu1,2, Yun-Dai Chen4, Keng Wu5, Guifu Wu6, Kaihong Chen7, Jianfeng Ye8, Yan Liang9, Xinwu Feng10, Shaohong Dong11, Qiming Wu12, Xianhua Ye13, Hesong Zeng14, http://orcid.org/0000-0001-5959-8367Minzhou Zhang15, Min Dai16,...
Hydration for prevention of kidney injury after primary coronary intervention for acute myocardial infarction: a randomised clinical trial
Hydration for prevention of kidney injury after primary coronary intervention for acute myocardial infarction: a randomised clinical trial http://orcid.org/0000-0003-2224-4885Yong Liu1,2, Ning Tan1,2, Yong Huo3, Shiqun Chen1,2, Jin Liu1,2, Yun-Dai Chen4, Keng Wu5, Guifu Wu6, Kaihong Chen7, Jianfeng Ye8, Yan Liang9, Xinwu Feng10, Shaohong Dong11, Qiming Wu12, Xianhua Ye13, Hesong Zeng14, http://orcid.org/0000-0001-5959-8367Minzhou Zhang15, Min Dai16,...
DAA Treatment and Fibrosis Regression After HCV Eradication
Abstract and Introduction Abstract Limited data are currently available regarding fibrosis progression after hepatitis C virus (HCV) eradication. The goal of the present study was to evaluate the effects of HCV eradication on liver stiffness measurements (LSMs), aspartate aminotransferase/platelet ratio index (APRI) scores, fibrosis-4(FIB-4) scores, chitinase-3-like protein 1 (CHI3L1) levels and Golgi protein 73 (GP73) levels in patients with chronic hepatitis C (CHC).
Hydration for prevention of kidney injury after primary coronary intervention for acute myocardial infarction: a randomised clinical trial
Hydration for prevention of kidney injury after primary coronary intervention for acute myocardial infarction: a randomised clinical trial http://orcid.org/0000-0003-2224-4885Yong Liu1, Ning Tan1, Yong Huo2, Shiqun Chen1, Jin Liu1, Yun-Dai Chen3, Keng Wu4, Guifu Wu5, Kaihong Chen6, Jianfeng Ye7, Yan Liang8, Xinwu Feng9, Shaohong Dong10, Qiming Wu11, Xianhua Ye12, Hesong Zeng13, http://orcid.org/0000-0001-5959-8367Minzhou Zhang14, Min Dai15, http://orcid.org/0000-0001-7973-0353Chong-Yang...
HBV pgRNA status can reveal the long‐term prognoses of chronic hepatitis B patients treated with nucleos(t)ide analogues
ORIGINAL PAPER Xiaoyuan Xu Corresponding Author E-mail address: Department of Infectious Diseases, Peking University First Hospital, Beijing, 100034 China Corresponding author Xiao‐Yuan Xu, MD Professor, Department of Infectious Diseases, Peking University First Hospital, 8 Xishiku Street, Beijing 100034, China. E‐mail: . Telephone: +86‐10‐83575787.
Association of Parenteral Anticoagulation Therapy With Outcomes in Chinese Patients Undergoing Percutaneous Coronary Intervention for Non-ST-Segment Elevation Acute Coronary Syndrome. | Acute Coronary Syndromes | JAMA Internal Medicine | JAMA Network
Key Points Question Is parenteral anticoagulation therapy beneficial for patients with non–ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention? Findings In this multicenter cohort study that included 6804 consecutive patients from 5 centers in China, parenteral anticoagulation therapy was not associated with lower all-cause death or myocardial infarction but was significantly associated with a higher risk of major bleeding.
Dynamic Greenland ice sheet driven by pCO<sub>2</sub> variations across the Pliocene Pleistocene transition
The climate model used in this study is the IPSL-CM5A GCM30. The atmosphere component is the LMDZ5A version of the LMDz model (including the ORCHIDEE land-surface model) with a resolution of 3.75°×1.875° and 39 vertical layers. More details about the physical parameterization can be found in30,46. The ocean model is NEMOv3.247, which integrates the dynamical model OPA, the LIM2 sea ice model and the PISCES biogeochemical model.
Effect of Metoprolol Succinate in Patients with Stable Angina and Elevated Heart Rate Receiving Low-Dose β-Blocker Therapy
Effect of Metoprolol Succinate in Patients with Stable Angina and Elevated Heart Rate Receiving Low-Dose ?-Blocker Therapy 1. Peking University First Hospital, 8 Xishiku Street., Xicheng District, Beijing, 100034; 2. Tianjin Chest Hospital, 93 Xian Road, Heping District, Tianjin, 30051; 3. The People's Hospital of Liaoning Province, 33 Wenyi Road, Shenhe District, Shenyang, Liaoning, 110016; 4.
Excessively High Hydration Volume May Not Be Associated With Decreased Risk of Contrast‐Induced Acute Kidney Injury After Percutaneous Coronary Intervention in Patients With Renal Insufficiency
Methods and Results Hydration volume ratios (hydration volume/weight; HV/W) were calculated in 1406 patients with renal insufficiency (estimated glomerular filtration rate [eGFR], <90 mL/min per 1.73 m2) undergoing percutaneous coronary intervention (PCI) with routine speed hydration (1 or 0.5 mL/kg per hour). We investigated the relationship between hydration volume, risk of CI‐AKI (increase in serum creatinine ≥0.5 mg/dL or 25% within 48–72 hours), and prognosis.
Safe Limits of Contrast Vary With Hydration Volume for Prevention of Contrast-Induced Nephropathy After Coronary Angiography Among Patients With a Relatively Low Risk of Contrast-Induced Nephropathy
Methods and Results—The ratios of contrast volume-to-creatinine clearance (V/CrCl) and hydration volume to body weight (HV/W) were determined in patients undergoing cardiac catheterization. Receiver–operator characteristic curve analysis based on the maximum Youden index was used to identify the optimal cutoff for V/CrCl in all patients and in HV/W subgroups. Eighty-six of 3273 (2.6%) patients with mean CrCl 71.89±27.02 mL/min developed CIN.
Preprocedural N‐Terminal Pro‐Brain Natriuretic Peptide (NT‐proBNP) Is Similar to the Mehran Contrast‐Induced Nephropathy (CIN) Score in Predicting CIN Following Elective Coronary Angiography
Background N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) has been associated with important risk factors for contrast‐induced nephropathy (CIN). However, few studies have investigated the predictive value of NT‐proBNP itself. This study investigated whether levels of preprocedural NT‐proBNP could predict CIN after elective coronary angiography as effectively as the Mehran CIN score. Methods and Results We retrospectively observed 2248 patients who underwent elective coronary angiography.
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