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Ninib Baryawno on Muck Rack

Ninib Baryawno

As seen in: Nature, MDPI, Genome Biology, Cell Press
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Articles

Mesenchymal thymic niche cells enable regeneration of the adult thymus and T cell immunity - Nature Biotechnology

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By Johanna Hofmann Verified, Ninib Baryawno, Joel A. Spencer, Christian Burns, Konstantinos D Kokkaliaris, Peter V. Kharchenko
| Nature Verified
Abstract Thymic atrophy and the progressive immune decline that accompanies it is a major health problem, chronically with age and acutely with immune injury. No definitive solution is available. Here we demonstrate that one of the three mesenchymal cell subsets identified by single-cell analysis of human and mouse thymic stroma is a critical niche component for T lymphopoiesis.
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Recent Advances in Single-Cell RNA-Sequencing of Primary and Metastatic Clear Cell Renal Cell Carcinoma

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By Adele M. Alchahin, Ninib Baryawno, Ioanna Tsea
| MDPI
1. Introduction Renal cell carcinoma (RCC) encompasses a group of malignant tumors originating from the epithelium of the proximal part of the renal tubules. The most prevalent histological subtype is clear cell RCC (ccRCC), accounting for approximately 75–80% of all RCC cases, followed by papillary RCC (pRCC; 10–15%) and chromophobe RCC (5–10%) [1]. Among RCC patients, about one-third develop bone metastasis, with ccRCC being the most common subtype.
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Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses - Nature Communications

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By Shenglin Mei, Keyan Salari, fei chen, Evan Z. Macosko, Ninib Baryawno, Philip J. Saylor, Peter V. Kharchenko, Taghreed Hirz
| Nature Verified
Patient materials In accordance with the U.S. Common Rule and after Institutional Review Board (IRB) approval, all human tissues were collected at Massachusetts General Hospital (MGH, Boston, MA) and carried out with institutional review board (IRB) approval (IRB#2003P000641). Written informed consents were obtained from all participants in the study.
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