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Norjin Zolboot

As seen in: BioRxiv, Cell Press
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Articles

MicroRNA mechanisms instructing Purkinje cell specification

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By Norjin Zolboot, Yao Xiao, Jessica X. Du, Marwan Ghanem, Su Yeun Choi, Miranda J. Junn, Federico Zampa, Zeyi Huang, Ian MacRae, Ian Macrae, Giordano Lippi
| Cell Press Verified
STAR★Methods REAGENT or RESOURCESOURCEIDENTIFIER Antibodies Anti-AGO2 for CLIP-seq Eclipse Bioinnovations N/A Rat anti-TNRC6ABC (clone 7A9) Sigma Cat#MABE1919; RRID: AB_3675909 Rabbit anti-GW182 (TNRC6A) for western blot Sigma Cat#G5922; RRID: AB_10603489 Rabbit anti-AGO1 for western blot Cell Signaling Technology Cat#D84G10; RRID:AB_2616013 Rabbit anti-AGO2 for western blot Cell Signaling Technology Cat#2897S; RRID:AB_2096291 Rabbit anti-HA Cell Signaling Technology Cat#C29F4;...
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MicroRNAs are necessary for the emergence of Purkinje cell identity

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By Yao Xiao, Jessica X. Du, Marwan Ghanem, Norjin Zolboot
| BioRxiv
Abstract Brain computations are dictated by the unique morphology and connectivity of neuronal subtypes, features established by closely timed developmental events. MicroRNAs (miRNAs) are critical for brain development, but current technologies lack the spatiotemporal resolution to determine how miRNAs instruct the steps leading to subtype identity. Here, we developed new tools to tackle this major gap.
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