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Nural Cokcetin

As seen in: CNN, Yahoo News Australia, ABC News (Australia), Stuff.co.nz, The Conversation, Medical Xpress, BioRxiv, ScienceAlert, eLife, Freethink
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Articles

Fast evolution of SOS-independent multi-drug resistance in bacteria

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By Le Fu Zhang, Yunpeng Guan, Nural Cokcetin, YuenYee Cheng
| eLife
eLife Assessment This study presents a valuable observation of how deletion of a major repair protein in bacteria can facilitate the rise of mutations that confer resistance against a range of different antibiotics. The data presented are convincing, and the authors addressed the concerns raised by the reviewers in their resubmission, improving the strength of their findings.
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Fast Evolution of SOS-Independent Multi-Drug Resistance in Bacteria

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By Le Fu Zhang, Yunpeng Guan, Nural Cokcetin, Amy L. Bottomley
| BioRxiv
Abstract The killing mechanism of many antibiotics involves the induction of DNA damage, either directly or indirectly, which triggers the SOS response. RecA, the master regulator of the SOS response, plays a crucial role in driving the evolution of resistance to fluoroquinolone antibiotics treated with a single dose of ciprofloxacin. However, the precise roles of RecA and SOS responses in the development of resistance under short-term β-lactam exposure remain unclear.
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Australian ant honey inhibits tough pathogens, new research shows

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By Nural Cokcetin, Kenya E. Fernandes, Danny Ulrich, Andrew Dong, Dee A. Carter
| Freethink
The medicinal value and potent antimicrobial activity of honey has been a topic of considerable interest in recent years, particularly in light of the alarming rise in antibiotic resistance. While most honey comes from honey bees (Apis mellifera), other insects such as stingless bees, wasps and even ants can produce honey-like products from plant nectar. One of these insects is the honeypot ant Camponotus inflatus, found throughout the central desert region of Australia.
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