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Özgün Doga Asik on Muck Rack

Özgün Doga Asik

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Articles

Direct visualization of native GSDMD pores reveals lipid-driven stabilization during pyroptosis

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By Feng Jiang, Antoine Diez, Juncheng Yao, Shirin Kappelhoff, Michael Holtmannspötter, Stefan Schaefer, Eleonora Margheritis, Özgün Doga Asik, Nadine Gehle, Hannah Veit, John S.H. Danial, Rico Franzkoch, Sebastian Strauss, Jonatan Alvelid, Agnes Koerfer, Christian Eggeling, Olympia E. Psathaki, Ralf Jungmann, Rainer Kurre, Gerhard Hummer, Jacob Piehler, Katia Cosentino
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Gasdermin D (GSDMD) executes pyroptosis by forming membrane pores, yet how these structures assemble and are regulated in cells has remained technically inaccessible.
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