P. Evans on Muck Rack

P. Evans

Kingston
As seen in: Color Research & Application, Nature, Wiley Online Library, ESPN, ACS Publications, American Chemical Society, Science Magazine, Royal Society of Chemistry, AIP Publishing, The Bone & Joint Journal and
Welsh Chemist and Sports Fan (These are my personal views)
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Articles

Stereospecific Transition‐Metal‐Free Alkylation of Chiral Non‐Racemic Secondary Tosylates with Cyanohydrins: Convenient Access to Enantiomerically Enriched α‐Tertiary Ketones

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By Jinjin Ma, Hui Li, Jadab Majhi, P. Evans
| Wiley Online Library
Enantioenriched α-tertiary ketones are key structural motifs in natural products, pharmaceuticals, and agrochemicals, and serve as versatile intermediates for constructing stereochemically complex molecules (Scheme 1a).[1-5] Despite significant advances in enantioselective enolate alkylation, the stereoselective synthesis of acyclic α-tertiary ketones—particularly those bearing unactivated alkyl substituents—remains a formidable challenge (Scheme 1b).[6-10] A central problem is the propensity...
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Stereospecific Transition‐Metal‐Free Alkylation of Chiral Non‐Racemic Secondary Tosylates with Cyanohydrins: Convenient Access to Enantiomerically Enriched α‐Tertiary Ketones

|
By Jinjin Ma, Hui Li, Jadab Majhi, P. Evans
| Wiley Online Library
Enantioenriched α-tertiary ketones are key structural motifs in natural products, pharmaceuticals, and agrochemicals, and serve as versatile intermediates for constructing stereochemically complex molecules (Scheme 1a).[1-5] Despite significant advances in enantioselective enolate alkylation, the stereoselective synthesis of acyclic α-tertiary ketones—particularly those bearing unactivated alkyl substituents—remains a formidable challenge (Scheme 1b).[6-10] A central problem is the propensity...
Open in Who Shared Issue with article?

Stereoselective transition metal-catalyzed [(2+2)+1] and [(2+2)+2] carbocyclization reactions using 1,6-enynes with 1,1-disubstituted olefins: construction of quaternary centers

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By P. Evans
| Royal Society of Chemistry
Stereoselective transition metal-catalyzed [(2+2)+1] and [(2+2)+2] carbocyclization reactions using 1,6-enynes with 1,1-disubstituted olefins: construction of quaternary centers Transition metal-catalyzed carbocyclization reactions provide a powerful method for the stereoselective assembly of complex, highly substituted (poly)cyclic scaffolds.
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