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Articles by P. Sun
NIR-II photothermal therapy mediated by polymer-based nanoparticles to enhance checkpoint inhibitor immunotherapy for inhibiting lymph node metastasis in oral squamous cell carcinoma
Oral Squamous Cell Carcinoma (OSCC) is a prevalent malignancy with a high rate of recurrence and metastasis, which are the primary reasons for its low five-year survival rate [1]. Despite significant advancements in early detection and treatment modalities, patients with OSCC often have poor prognoses owing to the aggressive nature of the disease and its propensity to metastasize [2].
Parameter selection and experimental study of the rock particle crushing effect using an image-based method
IdiomacatalàDeutschEnglishespañoleuskarafrançaisgalegoitalianoportuguêsromână
The stone powder wall shaping mechanism on machine-made sand
IdiomacatalàDeutschEnglishespañoleuskarafrançaisgalegoitalianoportuguêsromână
SMART START WITH TISLELIZUMAB AS THE FRONT‐LINE TREATMENT IN PATIENTS WITH HIGH‐RISK STAGE IIB AND ADVANCED‐STAGE CLASSICAL HODGKIN LYMPHOMA
Introduction: Around 10%–30% of classical Hodgkin's lymphoma(cHL) will relapse or refract after treatment with traditional cytotoxic drug-based chemotherapy, meanwhile the chemotherapy-related toxicity cannot be ignored. In order to balance efficacy and toxicity, we use the concept of ‘Smart Start’ to explore the efficacy and safety of tislelizumab sequentially combined with AVD regimen in the first-line treatment of cHL in phase II study (NCT04843267).
Limits on gas impermeability of graphene
Abstract Despite being only one-atom thick, defect-free graphene is considered to be completely impermeable to all gases and liquids1,2,3,4,5,6,7,8,9,10. This conclusion is based on theory3,4,5,6,7,8 and supported by experiments1,9,10 that could not detect gas permeation through micrometre-size membranes within a detection limit of 105 to 106 atoms per second.
New Ca. Liberibacter psyllaurous haplotype resurrected from a 49-year-old specimen of Solanum umbelliferum: a native host of the psyllid vector
Abstract Over the last century, repeated emergence events within the Candidatus Liberibacter taxon have produced pathogens with devastating effects. Presently, our knowledge of Ca. Liberibacter diversity, host associations, and interactions with vectors is limited due to a focus on studying this taxon within crops. But to understand traits associated with pathogen emergence it is essential to study pathogen diversity in wild vegetation as well.
Rapid onset of conjunctivitis associated with overdosing of erlotinib
What is known and objective Erlotinib is one of the epidermal growth factor receptor (EGFR) inhibitors and is widely used as a targeted therapy for advanced non-small-cell lung cancer (NSCLC). There are a few reports regarding ocular adverse effects of erlotinib. Herein, we report a case of rapid onset of ocular toxicity associated with overdosing of erlotinib. A 72-year-old male with metastatic NSCLC developed conjunctivitis after accidentally taking erlotinib at a dosage of 300 mg/day for 4 days.
Rapid onset of conjunctivitis associated with overdosing of erlotinib
Erlotinib is one of the epidermal growth factor receptor (EGFR) inhibitors and is widely used as a targeted therapy for advanced non‐small‐cell lung cancer (NSCLC). There are a few reports regarding ocular adverse effects of erlotinib. Herein, we report a case of rapid onset of ocular toxicity associated with overdosing of erlotinib. A 72‐year‐old male with metastatic NSCLC developed conjunctivitis after accidentally taking erlotinib at a dosage of 300 mg/day for 4 days.
The Twelve Days of Christmas: A Peek-Through Picture Book by Britta Teckentrup
Publisher: Doubleday Books for Young ReadersFormats: HardcoverPurchase: Powell’s | Amazon Britta Teckentrup has created a wonderful interpretation of a fun, traditional holiday carol with The Twelve Days of Christmas: A Peek-Through Picture Book. This delightfully illustrated book will be a family favorite in no time.
Impact of screening mammography on mortality from breast cancer before age 60 in women 40 to 49 years of age
Whether screening mammography programs should include women as young as 40 is controversial. Guidelines vary, but in 2009, the U.S. Preventive Services Task Force recommended against routine mammograms for women in their 40s 1. Recently, guidelines in British Columbia changed to reverse the prior position that mammography be offered annually to all women between the ages of 40 and 50 2. In Switzerland, it has been proposed that routine screening mammography be discontinued 3.
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