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Palash C. Maity

As seen in: Nature, PNAS
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Articles

Defective cell-autonomous signalling and antigenic polyreactivity of B-cell receptors from chronic lymphocytic leukaemia stereotyped subset 1 - Nature Communications

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By Paolo Cocomazzi, Claudia Minici, Marco Patrone, Luca Broggini, Ioannis Sarrigeorgiou, Peggy Lymberi, Georgios Petrakis, Triantafyllia Koletsa, Andreas Agathangelidis, Hassan Jumaa Verified, Palash C. Maity, Paolo Ghia, Kostas Stamatopoulos, Can Akpınaroğlu, Michela Frenquelli
| Nature Verified
Abstract A shared feature of B-cell receptors (BCRs) expressed on neoplastic B cells from patients with chronic lymphocytic leukaemia (CLL) concerns their continual activation of intracellular signalling without requiring external antigens. This autonomous signalling mechanism has previously been demonstrated to arise from BCR-BCR homotypic interactions in three distinct stereotyped CLL subsets (2, 4 and 169).
Open in Who Shared Issue with article?

IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling

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By Marvyn T Koning, Marc Young, Palash C. Maity, Mayas Bilal
| PNAS Verified
Research Article Palash C. Maity, Mayas Bilal, Marvyn T. Koning, Marc Young, View ORCID ProfileCornelis A. M. van Bergen, Valerio Renna, Antonella Nicolò, Moumita Datta, Eva Gentner-Göbel, Rob S. Barendse, Sebastiaan F. Somers, Ruben A. L. de Groen, Joost S. P. Vermaat, Daniela Steinbrecher, Christof Schneider, Eugen Tausch, Tamara Bittolo, Riccardo Bomben, Andrea Nicola Mazzarello, Giovanni del Poeta, Wilma G. M. Kroes, J. Tom van Wezel, Katharina Imkeller, Christian E.
Open in Who Shared Issue with article?
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