Parijat Das

Keywords Omega transaminases rational design biotransformation X-ray crystallography structural biology enzyme structure enzyme catalysis structure-function Abbreviations TA (Transaminase) ω-TA (Omega transaminase) PLP (Pyridoxal 5ʹ-phosphate) PMP (Pyridoxamine 5ʹ-phosphate) PGBC (Phosphate group binding cup) (R)-PAC ((R)-phenylacetylcarbinol) RMSD (Root mean square deviation) (S)-MBA ((S)-methylbenzylamine) TTC (Triphenyl tetrazolium chloride) Introduction: Transaminases (TAs) or...

CONFLICT OF INTEREST STATEMENT The authors declare no competing interests. Supporting Information Filename Description pro70038-sup-0001-Supinfo.pdfPDF document, 36.8 MB Supplementary Table S1. Contains the data collection and refinement statistics of AtGDH crystal structures. Supplementary Table S2. Contains cryo-EM data collection and refinement statistics. Supplementary Table S3. Contains the measured active site opening in AtGDH quaternary structures. Supplementary Table S4.