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Sequencing ADCs and Targeted Therapies With Radiation in Breast Cancer
As antibody-drug conjugates (ADCs) and novel targeted therapies migrate into earlier lines of breast cancer care, the traditional radiation oncology playbook is being rewritten. While agents like fam-trastuzumab deruxtecan-nxki (Enhertu) and sacituzumab govitecan-hziy (Trodelvy) offer unprecedented systemic control, their integration with regional radiation therapy requires a sophisticated balance of timing and toxicity surveillance.
De-escalated radiotherapy for HER2-overexpressing breast cancer patients with 1-3 positive lymph nodes undergoing anti-HER2 targeted therapy
1 Introduction Patients with 1-3 axillary lymph node metastases and a clinical stage of N1 constitute approximately 25%–30% of early operable breast cancer cases. Radiotherapy is one of the essential components of comprehensive breast cancer treatment.
VIDEO: Disparities in radiation oncology are ‘a massive problem’
Source/Disclosures Source: Healio Interview Disclosures: Healio was unable to determine relevant financial disclosures at the time of publication. Source/Disclosures Source: Healio Interview Disclosures: Healio was unable to determine relevant financial disclosures at the time of publication. We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.
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