Pathacha Suksakit on Muck Rack

Pathacha Suksakit

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Articles

Machine learning–based cfDNA fragmentation profiling using automated capillary electrophoresis for early detection of hepatocellular carcinoma - Communications Medicine

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By Sasimol Udomruk, Songphon Sutthitthasakul, Nuttida Bunsermvicha, Kanokwan Pinyopornpanish, Dumnoensun Pruksakorn, Phasit Charoenkwan, Petlada Yongpitakwattana, Kanlaya Khounkaew, Thanapak Jaimalai, Treephum Duangsan, Santhasiri Orrapin, Sutpirat Moonmuang, Pitiporn Noisagul, Arnat Pasena, Pathacha Suksakit, Ratikorn Gamngoen, Pimpisa Teeyakasem, Chaiyut Charoentum, Sarawut Kongkarnka, Worakitti Lapisatepun, Parunya Chaiyawat
| Nature
Abstract Early detection of hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited sensitivity of current surveillance tools, alpha-fetoprotein (AFP) and ultrasound. Recently, cell-free DNA (cfDNA) fragmentation analysis has shown promise in cancer detection; however, current sequencing-based approaches remain costly and unsuitable for large-scale screening.
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