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Paul Brogan on Muck Rack

Paul Brogan

New Hampshire
As seen in: Nature, Wiley Online Library, RTÉ, AJNR Podcasts

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Paul Brogan’s Biography

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Born in New Hampshire, I have spent most of my life living in this still bucolic New England State.

I graduated from Bishop Brady High School and attended Plymouth State University in New Hampshire.

During my working career I worked at such traditional organizations such as the State of New Hampshire, Blue Cross and Blue Shield and Concord Group Insurance as well as New Hampshire Legal Assistance. Less traditional positions were found at such diverse places as The Concord Theatre, CBS Televi…

Paul Brogan’s Journalist Portfolio

Paul Brogan Book Presentation at Gibsons Bookstore - May 9, 2019

Paul Brogan Book Presentation at Gibsons Bookstore - May 9, 2019

Author Paul Brogan talks about his new book, "The Concord Theatre and Concord's Love Affair with the Movies" …

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Articles

Neuroimaging Findings and Treatment Update for Neuroinflammation, Autoinflammation, Splenomegaly, and Anemia, a Novel Autoinflammatory Disorder Caused by Bi-Allelic Variants in IRAK4

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By Fiona Price-Kuehne, Paul Brogan
| AJNR Podcasts
ABBREVIATIONS: HSV herpes simplex virus IL-6 interleukin 6 IL-6R IL-6 receptor IRAK4 interleukin 4 receptor-associated kinase MMF mycophenolate mofetil MTL medial temporal lobe NASA neuroinflammation, autoinflammation, splenomegaly, and anemia sc subcutaneous TLR toll-like receptor In 2023, we described a novel, severe autoinflammatory disorder characterized by neuroinflammation, autoinflammation, splenomegaly, and anemia (NASA) caused by a bi-allelic combination of a null plus hypomorphic...
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Preclinical evaluation of lentiviral gene therapy for adenosine deaminase 2 deficiency (DADA2): engraftment efficiency and biodistribution in humanised NBSGW mice | Gene Therapy

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By Ying Hong, Emma Morris, Paul Brogan
| Nature Verified
Abstract Adenosine deaminase type 2 deficiency (DADA2) is caused by bi-allelic loss-of-function mutations in ADA2. While anti-TNF therapy is effective for the autoinflamatory and vasculitic components of the disease it does not correct marrow failure or immunodeficiency. Allogeneic stem cell transplantation (HSCT) offers a potential cure but is limited by challenges such as graft-versus-host-disease and donor availability.
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The pathogenesis, clinical presentations and treatment of monogenic systemic vasculitis - Nature Reviews Rheumatology

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By Ivona Aksentijevich, Paul Brogan
| Nature Verified
Abstract Many monogenic autoinflammatory diseases, including DADA2 (deficiency of adenosine deaminase 2), HA20 (haploinsufficiency of A20), SAVI (STING-associated vasculopathy with onset in infancy), COPA syndrome, LAVLI (LYN kinase-associated vasculopathy and liver fibrosis) and VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome, present predominantly with vasculitis and constitute a substantial subgroup of vasculitic conditions associated with a ‘probable aetiology’.
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Interview

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What was your first job as a journalist?

Writing film reviews for a company I worked at for 7 1/2 years.

Have you ever used a typewriter?

Learned to type on a typewriter and still find a certain level of comfort and pleasure in using one from time to time.

How is social media changing news?

Making it more immediate and instant but also skewing it at times and not always in the best way.