Paul Heinz

Abstract Cell-to-cell signaling between niche and stem cells regulates tissue renewal. While the identity of many mediating factors is known, it is largely unknown whether stem cells optimize their receptiveness to niche signals according to the niche organization. Here, we show that Lgr5+ small intestinal stem cells (ISCs) regulate the morphology and orientation of their secretory apparatus to match the niche architecture, and to increase transport efficiency of niche signal receptors.

I've seen an argument on right-leaning sites pointing out that BLM is racist against white people. While BLM is certainly guilty of that, the movement is actually racist in the old-fashioned, Ku Klux Klan way, as mentored through a century of life by Old Mr. Jim Crow himself. It's racist, in other words, not so much to white people, but to the black people it claims to champion. It takes as a first position a concept of the African-American male as without agency.