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Pavlína Bartíková on Muck Rack

Pavlína Bartíková

As seen in: Nature, MDPI
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Articles

Human epidermal Langerhans cells induce tolerance and hamper T cell function upon tick-borne pathogen transmission - Nature Communications

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By Johanna Strobl, Lisa Kleissl, Julia Eder, Tobias Frey, Laura Gail, Aglaja Kopf, Pavlína Bartíková, Klaus Schmetterer, Herbert Strobl, Hannes Stockinger, Michiel Wijnveld, Sally Conolly
| Nature Verified
Abstract Arthropods are ancient vectors of infectious disease that alter the immune environment of the skin during feeding. The epidermis and its immune sentinels, including Langerhans cells, are critical for protection against ectoparasitic arthropods such as ticks. Here, we investigate how human Langerhans cells respond to clinical and experimental tick bites and concomitant infection with the tick-borne bacterium Borrelia burgdorferi.
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Discovery of the Role of Tick Salivary Glands in Enhancement of Virus Transmission—Beginning of an Exciting Story

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By Maria Kazimirova, Pavlína Bartíková
| MDPI
Abstract : There is increasing evidence that arthropod-borne pathogens exploit saliva of their vectors during the transmission process to vertebrate hosts. Extensive research of the composition of tick saliva and its role in blood-feeding and transmission of pathogens started in the late 1980s and led to a number of discoveries on the composition and function of salivary molecules, some of which are associated with pathogen transmission. The study by Jones et al.
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